| Saturday, 7 September 2024 |
| Anselmians 2nd XV | 21 | 11 | Sandbach 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | 54 | 12 | Firwood Waterloo 2nd XV |
| Eagle | 26 | 12 | Sale FC Vikings |
| Eccles 2nd XV | 56 | 14 | Kendal 2nd XV |
| Preston Grasshoppers 3rd XV | 50 | 0 | Vale of Lune 2nd XV |
| Stockport 2nd XV | 33 | 0 | Aldwinians 2nd XV |
| Saturday, 14 September 2024 |
| Aldwinians 2nd XV | v | Sale FC Vikings |
| Anselmians 2nd XV | v | Eagle |
| Eccles 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Sandbach 2nd XV | v | Preston Grasshoppers 3rd XV |
| Stockport 2nd XV | v | Firwood Waterloo 2nd XV |
| Vale of Lune 2nd XV | v | Kendal 2nd XV |
| Saturday, 21 September 2024 |
| Birkenhead Park Wanderers (2nd XV) | v | Vale of Lune 2nd XV |
| Eagle | v | Aldwinians 2nd XV |
| Kendal 2nd XV | v | Sandbach 2nd XV |
| Preston Grasshoppers 3rd XV | v | Anselmians 2nd XV |
| Sale FC Vikings | v | Firwood Waterloo 2nd XV |
| Stockport 2nd XV | v | Eccles 2nd XV |
| Saturday, 28 September 2024 |
| Anselmians 2nd XV | v | Kendal 2nd XV |
| Eccles 2nd XV | v | Sale FC Vikings |
| Firwood Waterloo 2nd XV | v | Aldwinians 2nd XV |
| Preston Grasshoppers 3rd XV | v | Eagle |
| Sandbach 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Vale of Lune 2nd XV | v | Stockport 2nd XV |
| Saturday, 5 October 2024 |
| Eagle | v | Vale of Lune 2nd XV |
| Eccles 2nd XV | v | Firwood Waterloo 2nd XV |
| Saturday, 12 October 2024 |
| Aldwinians 2nd XV | v | Eccles 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | v | Anselmians 2nd XV |
| Firwood Waterloo 2nd XV | v | Eagle |
| Preston Grasshoppers 3rd XV | v | Kendal 2nd XV |
| Sale FC Vikings | v | Vale of Lune 2nd XV |
| Stockport 2nd XV | v | Sandbach 2nd XV |
| Saturday, 19 October 2024 |
| Aldwinians 2nd XV | v | Vale of Lune 2nd XV |
| Anselmians 2nd XV | v | Stockport 2nd XV |
| Firwood Waterloo 2nd XV | v | Sandbach 2nd XV |
| Kendal 2nd XV | v | Eagle |
| Preston Grasshoppers 3rd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Saturday, 26 October 2024 |
| Aldwinians 2nd XV | v | Sandbach 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | v | Kendal 2nd XV |
| Eagle | v | Eccles 2nd XV |
| Firwood Waterloo 2nd XV | v | Vale of Lune 2nd XV |
| Sale FC Vikings | v | Anselmians 2nd XV |
| Stockport 2nd XV | v | Preston Grasshoppers 3rd XV |
| Saturday, 9 November 2024 |
| Anselmians 2nd XV | v | Aldwinians 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | v | Eagle |
| Eccles 2nd XV | v | Sandbach 2nd XV |
| Kendal 2nd XV | v | Stockport 2nd XV |
| Preston Grasshoppers 3rd XV | v | Sale FC Vikings |
| Saturday, 16 November 2024 |
| Firwood Waterloo 2nd XV | v | Anselmians 2nd XV |
| Preston Grasshoppers 3rd XV | v | Aldwinians 2nd XV |
| Sale FC Vikings | v | Kendal 2nd XV |
| Sandbach 2nd XV | v | Vale of Lune 2nd XV |
| Stockport 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Saturday, 23 November 2024 |
| Anselmians 2nd XV | v | Eccles 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | v | Sale FC Vikings |
| Kendal 2nd XV | v | Aldwinians 2nd XV |
| Preston Grasshoppers 3rd XV | v | Firwood Waterloo 2nd XV |
| Stockport 2nd XV | v | Eagle |
| Saturday, 30 November 2024 |
| Sandbach 2nd XV | v | Sale FC Vikings |
| Vale of Lune 2nd XV | v | Eccles 2nd XV |
| Saturday, 7 December 2024 |
| Aldwinians 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Eagle | v | Sandbach 2nd XV |
| Eccles 2nd XV | v | Preston Grasshoppers 3rd XV |
| Firwood Waterloo 2nd XV | v | Kendal 2nd XV |
| Sale FC Vikings | v | Stockport 2nd XV |
| Vale of Lune 2nd XV | v | Anselmians 2nd XV |
| Saturday, 14 December 2024 |
| Birkenhead Park Wanderers (2nd XV) | v | Eccles 2nd XV |
| Eagle | v | Anselmians 2nd XV |
| Firwood Waterloo 2nd XV | v | Stockport 2nd XV |
| Kendal 2nd XV | v | Vale of Lune 2nd XV |
| Preston Grasshoppers 3rd XV | v | Sandbach 2nd XV |
| Sale FC Vikings | v | Aldwinians 2nd XV |
| Saturday, 21 December 2024 |
| Aldwinians 2nd XV | v | Eagle |
| Anselmians 2nd XV | v | Preston Grasshoppers 3rd XV |
| Eccles 2nd XV | v | Stockport 2nd XV |
| Firwood Waterloo 2nd XV | v | Sale FC Vikings |
| Sandbach 2nd XV | v | Kendal 2nd XV |
| Vale of Lune 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Saturday, 4 January 2025 |
| Kendal 2nd XV | v | Anselmians 2nd XV |
| Vale of Lune 2nd XV | v | Eagle |
| Saturday, 11 January 2025 |
| Anselmians 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Eagle | v | Firwood Waterloo 2nd XV |
| Eccles 2nd XV | v | Aldwinians 2nd XV |
| Kendal 2nd XV | v | Preston Grasshoppers 3rd XV |
| Sandbach 2nd XV | v | Stockport 2nd XV |
| Vale of Lune 2nd XV | v | Sale FC Vikings |
| Saturday, 18 January 2025 |
| Birkenhead Park Wanderers (2nd XV) | v | Preston Grasshoppers 3rd XV |
| Eagle | v | Kendal 2nd XV |
| Sandbach 2nd XV | v | Firwood Waterloo 2nd XV |
| Stockport 2nd XV | v | Anselmians 2nd XV |
| Vale of Lune 2nd XV | v | Aldwinians 2nd XV |
| Saturday, 1 February 2025 |
| Anselmians 2nd XV | v | Sale FC Vikings |
| Eccles 2nd XV | v | Eagle |
| Kendal 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Preston Grasshoppers 3rd XV | v | Stockport 2nd XV |
| Sandbach 2nd XV | v | Aldwinians 2nd XV |
| Vale of Lune 2nd XV | v | Firwood Waterloo 2nd XV |
| Saturday, 8 February 2025 |
| Firwood Waterloo 2nd XV | v | Eccles 2nd XV |
| Sale FC Vikings | v | Sandbach 2nd XV |
| Saturday, 15 February 2025 |
| Aldwinians 2nd XV | v | Anselmians 2nd XV |
| Eagle | v | Birkenhead Park Wanderers (2nd XV) |
| Sale FC Vikings | v | Preston Grasshoppers 3rd XV |
| Sandbach 2nd XV | v | Eccles 2nd XV |
| Stockport 2nd XV | v | Kendal 2nd XV |
| Saturday, 22 February 2025 |
| Eccles 2nd XV | v | Vale of Lune 2nd XV |
| Saturday, 1 March 2025 |
| Aldwinians 2nd XV | v | Preston Grasshoppers 3rd XV |
| Anselmians 2nd XV | v | Firwood Waterloo 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | v | Stockport 2nd XV |
| Kendal 2nd XV | v | Sale FC Vikings |
| Vale of Lune 2nd XV | v | Sandbach 2nd XV |
| Saturday, 8 March 2025 |
| Aldwinians 2nd XV | v | Kendal 2nd XV |
| Eagle | v | Stockport 2nd XV |
| Eccles 2nd XV | v | Anselmians 2nd XV |
| Firwood Waterloo 2nd XV | v | Preston Grasshoppers 3rd XV |
| Sale FC Vikings | v | Birkenhead Park Wanderers (2nd XV) |
| Saturday, 22 March 2025 |
| Anselmians 2nd XV | v | Vale of Lune 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | v | Aldwinians 2nd XV |
| Kendal 2nd XV | v | Firwood Waterloo 2nd XV |
| Preston Grasshoppers 3rd XV | v | Eccles 2nd XV |
| Sandbach 2nd XV | v | Eagle |
| Stockport 2nd XV | v | Sale FC Vikings |
| Saturday, 5 April 2025 |
| Aldwinians 2nd XV | v | Stockport 2nd XV |
| Firwood Waterloo 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Kendal 2nd XV | v | Eccles 2nd XV |
| Sale FC Vikings | v | Eagle |
| Sandbach 2nd XV | v | Anselmians 2nd XV |
| Vale of Lune 2nd XV | v | Preston Grasshoppers 3rd XV |
| Saturday, 26 April 2025 |
| Aldwinians 2nd XV | v | Firwood Waterloo 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | v | Sandbach 2nd XV |
| Eagle | v | Preston Grasshoppers 3rd XV |
| Sale FC Vikings | v | Eccles 2nd XV |
| Stockport 2nd XV | v | Vale of Lune 2nd XV |