| Saturday, 26 September 2026 |
| Blackburn 2nd XV | 42 | 7 | Anselmians 2nd XV |
| Ellesmere Port | 24 | 33 | Birkenhead Park Wanderers (2nd XV) |
| Kendal 2nd XV | 69 | 19 | West Park (St Helens) 2nd XV |
| Manchester 2nd XV | 5 | 53 | Fylde Vandals |
| Rochdale 2nd XV | 46 | 16 | Vale of Lune 2nd XV |
| Widnes 2nd XV | Home Walkover | Kirkby Lonsdale RUFC Development XV |
| Saturday, 3 October 2026 |
| Birkenhead Park Wanderers (2nd XV) | 0 | 87 | Kendal 2nd XV |
| Blackburn 2nd XV | 39 | 32 | Ellesmere Port |
| Fylde Vandals | 69 | 17 | Vale of Lune 2nd XV |
| Manchester 2nd XV | 47 | 7 | Widnes 2nd XV |
| Rochdale 2nd XV | 29 | 35 | Anselmians 2nd XV |
| West Park (St Helens) 2nd XV | 50 | 55 | Kirkby Lonsdale RUFC Development XV |
| Saturday, 10 October 2026 |
| Birkenhead Park Wanderers (2nd XV) | 12 | 43 | Blackburn 2nd XV |
| Rochdale 2nd XV | 35 | 48 | Manchester 2nd XV |
| Vale of Lune 2nd XV | 26 | 37 | Anselmians 2nd XV |
| West Park (St Helens) 2nd XV | 21 | 21 | Ellesmere Port |
| Widnes 2nd XV | 30 | 5 | Kendal 2nd XV |
| Saturday, 17 October 2026 |
| Birkenhead Park Wanderers (2nd XV) | 29 | 26 | Kirkby Lonsdale RUFC Development XV |
| Ellesmere Port | 35 | 17 | Anselmians 2nd XV |
| Kendal 2nd XV | 26 | 12 | Blackburn 2nd XV |
| Manchester 2nd XV | 33 | 19 | West Park (St Helens) 2nd XV |
| Rochdale 2nd XV | 29 | 40 | Fylde Vandals |
| Vale of Lune 2nd XV | 50 | 19 | Widnes 2nd XV |
| Saturday, 24 October 2026 |
| Anselmians 2nd XV | Home Walkover | Fylde Vandals |
| Birkenhead Park Wanderers (2nd XV) | 7 | 31 | Manchester 2nd XV |
| Blackburn 2nd XV | 57 | 3 | Kirkby Lonsdale RUFC Development XV |
| Ellesmere Port | 39 | 0 | Kendal 2nd XV |
| West Park (St Helens) 2nd XV | 0 | 50 | Vale of Lune 2nd XV |
| Widnes 2nd XV | 38 | 24 | Rochdale 2nd XV |
| Saturday, 31 October 2026 |
| Fylde Vandals | 61 | 5 | Widnes 2nd XV |
| Kendal 2nd XV | 22 | 12 | Anselmians 2nd XV |
| Kirkby Lonsdale RUFC Development XV | 17 | 55 | Ellesmere Port |
| Manchester 2nd XV | 48 | 31 | Blackburn 2nd XV |
| Rochdale 2nd XV | 69 | 12 | West Park (St Helens) 2nd XV |
| Vale of Lune 2nd XV | Home Walkover | Birkenhead Park Wanderers (2nd XV) |
| Saturday, 7 November 2026 |
| Anselmians 2nd XV | v | Widnes 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | v | Rochdale 2nd XV |
| Blackburn 2nd XV | v | Vale of Lune 2nd XV |
| Ellesmere Port | v | Manchester 2nd XV |
| Kendal 2nd XV | v | Kirkby Lonsdale RUFC Development XV |
| West Park (St Helens) 2nd XV | v | Fylde Vandals |
| Saturday, 14 November 2026 |
| Fylde Vandals | v | Kirkby Lonsdale RUFC Development XV |
| Saturday, 21 November 2026 |
| Birkenhead Park Wanderers (2nd XV) | v | Anselmians 2nd XV |
| Blackburn 2nd XV | v | West Park (St Helens) 2nd XV |
| Ellesmere Port | v | Widnes 2nd XV |
| Kendal 2nd XV | v | Fylde Vandals |
| Kirkby Lonsdale RUFC Development XV | v | Rochdale 2nd XV |
| Manchester 2nd XV | v | Vale of Lune 2nd XV |
| Saturday, 28 November 2026 |
| Anselmians 2nd XV | v | West Park (St Helens) 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | v | Widnes 2nd XV |
| Blackburn 2nd XV | v | Fylde Vandals |
| Ellesmere Port | v | Rochdale 2nd XV |
| Kendal 2nd XV | v | Vale of Lune 2nd XV |
| Manchester 2nd XV | v | Kirkby Lonsdale RUFC Development XV |
| Saturday, 5 December 2026 |
| Fylde Vandals | v | Ellesmere Port |
| Manchester 2nd XV | v | Anselmians 2nd XV |
| Rochdale 2nd XV | v | Kendal 2nd XV |
| Vale of Lune 2nd XV | v | Kirkby Lonsdale RUFC Development XV |
| West Park (St Helens) 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Widnes 2nd XV | v | Blackburn 2nd XV |
| Saturday, 12 December 2026 |
| Anselmians 2nd XV | v | Vale of Lune 2nd XV |
| Blackburn 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Ellesmere Port | v | West Park (St Helens) 2nd XV |
| Kendal 2nd XV | v | Widnes 2nd XV |
| Kirkby Lonsdale RUFC Development XV | v | Fylde Vandals |
| Manchester 2nd XV | v | Rochdale 2nd XV |
| Saturday, 9 January 2027 |
| Vale of Lune 2nd XV | v | Rochdale 2nd XV |
| Widnes 2nd XV | v | Kirkby Lonsdale RUFC Development XV |
| Saturday, 16 January 2027 |
| Anselmians 2nd XV | v | Rochdale 2nd XV |
| Ellesmere Port | v | Blackburn 2nd XV |
| Kendal 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Kirkby Lonsdale RUFC Development XV | v | West Park (St Helens) 2nd XV |
| Vale of Lune 2nd XV | v | Fylde Vandals |
| Widnes 2nd XV | v | Manchester 2nd XV |
| Saturday, 23 January 2027 |
| Anselmians 2nd XV | v | Ellesmere Port |
| Blackburn 2nd XV | v | Kendal 2nd XV |
| Fylde Vandals | v | Rochdale 2nd XV |
| Kirkby Lonsdale RUFC Development XV | v | Birkenhead Park Wanderers (2nd XV) |
| West Park (St Helens) 2nd XV | v | Manchester 2nd XV |
| Widnes 2nd XV | v | Vale of Lune 2nd XV |
| Saturday, 6 February 2027 |
| Anselmians 2nd XV | v | Fylde Vandals |
| Kendal 2nd XV | v | Ellesmere Port |
| Kirkby Lonsdale RUFC Development XV | v | Blackburn 2nd XV |
| Manchester 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Rochdale 2nd XV | v | Widnes 2nd XV |
| Vale of Lune 2nd XV | v | West Park (St Helens) 2nd XV |
| Saturday, 13 February 2027 |
| Anselmians 2nd XV | v | Kendal 2nd XV |
| Blackburn 2nd XV | v | Manchester 2nd XV |
| Ellesmere Port | v | Kirkby Lonsdale RUFC Development XV |
| Vale of Lune 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| West Park (St Helens) 2nd XV | v | Rochdale 2nd XV |
| Widnes 2nd XV | v | Fylde Vandals |
| Saturday, 20 February 2027 |
| Fylde Vandals | v | West Park (St Helens) 2nd XV |
| Kirkby Lonsdale RUFC Development XV | v | Kendal 2nd XV |
| Manchester 2nd XV | v | Ellesmere Port |
| Rochdale 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Vale of Lune 2nd XV | v | Blackburn 2nd XV |
| Widnes 2nd XV | v | Anselmians 2nd XV |
| Saturday, 27 February 2027 |
| Anselmians 2nd XV | v | Blackburn 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | v | Ellesmere Port |
| Fylde Vandals | v | Manchester 2nd XV |
| West Park (St Helens) 2nd XV | v | Kendal 2nd XV |
| Saturday, 6 March 2027 |
| Anselmians 2nd XV | v | Kirkby Lonsdale RUFC Development XV |
| Birkenhead Park Wanderers (2nd XV) | v | Fylde Vandals |
| Blackburn 2nd XV | v | Rochdale 2nd XV |
| Ellesmere Port | v | Vale of Lune 2nd XV |
| Kendal 2nd XV | v | Manchester 2nd XV |
| West Park (St Helens) 2nd XV | v | Widnes 2nd XV |
| Saturday, 13 March 2027 |
| Fylde Vandals | v | Blackburn 2nd XV |
| Kirkby Lonsdale RUFC Development XV | v | Manchester 2nd XV |
| Rochdale 2nd XV | v | Ellesmere Port |
| Vale of Lune 2nd XV | v | Kendal 2nd XV |
| West Park (St Helens) 2nd XV | v | Anselmians 2nd XV |
| Widnes 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Saturday, 3 April 2027 |
| Anselmians 2nd XV | v | Manchester 2nd XV |
| Birkenhead Park Wanderers (2nd XV) | v | West Park (St Helens) 2nd XV |
| Blackburn 2nd XV | v | Widnes 2nd XV |
| Ellesmere Port | v | Fylde Vandals |
| Kendal 2nd XV | v | Rochdale 2nd XV |
| Kirkby Lonsdale RUFC Development XV | v | Vale of Lune 2nd XV |
| Saturday, 10 April 2027 |
| Anselmians 2nd XV | v | Birkenhead Park Wanderers (2nd XV) |
| Fylde Vandals | v | Kendal 2nd XV |
| Rochdale 2nd XV | v | Kirkby Lonsdale RUFC Development XV |
| Vale of Lune 2nd XV | v | Manchester 2nd XV |
| West Park (St Helens) 2nd XV | v | Blackburn 2nd XV |
| Widnes 2nd XV | v | Ellesmere Port |
| Saturday, 17 April 2027 |
| Fylde Vandals | v | Birkenhead Park Wanderers (2nd XV) |
| Kirkby Lonsdale RUFC Development XV | v | Anselmians 2nd XV |
| Manchester 2nd XV | v | Kendal 2nd XV |
| Rochdale 2nd XV | v | Blackburn 2nd XV |
| Vale of Lune 2nd XV | v | Ellesmere Port |
| Widnes 2nd XV | v | West Park (St Helens) 2nd XV |