| Saturday, 3 September 2022 |
| Colne & Nelson 2nd XV | 22 | 5 | Clitheroe 2nd XV |
| Preston Grasshoppers 4th XV | 15 | 26 | Burnley 2nd XV |
| Preston Grasshoppers 5th XV | 12 | 72 | Garstang Blues (2nd XV) |
| Saturday, 10 September 2022 |
| Fleetwood Wyresiders (2nd XV) | 50 | 5 | Colne & Nelson 2nd XV |
| Garstang RFC 3rd XV Men | 0 | 8 | Fylde Vandals (4th XV) |
| Preston Grasshoppers 4th XV | 31 | 24 | Clitheroe 2nd XV |
| Saturday, 17 September 2022 |
| Clitheroe 2nd XV | 17 | 34 | Fleetwood Wyresiders (2nd XV) |
| Garstang Blues (2nd XV) | Home Walkover | Fylde Vandals (4th XV) |
| Garstang RFC 3rd XV Men | 0 | 8 | Colne & Nelson 2nd XV |
| Preston Grasshoppers 5th XV | 25 | 17 | Preston Grasshoppers 4th XV |
| Saturday, 24 September 2022 |
| Burnley 2nd XV | Home Walkover | Fylde Vandals (4th XV) |
| Garstang RFC 3rd XV Men | 35 | 31 | Clitheroe 2nd XV |
| Preston Grasshoppers 4th XV | 27 | 36 | Fleetwood Wyresiders (2nd XV) |
| Saturday, 1 October 2022 |
| Clitheroe 2nd XV | 0 | 50 | Vale of Lune 3rd XV |
| Colne & Nelson 2nd XV | 7 | 62 | Garstang Blues (2nd XV) |
| Fleetwood Wyresiders (2nd XV) | 54 | 28 | Garstang RFC 3rd XV Men |
| Saturday, 8 October 2022 |
| Vale of Lune 3rd XV | 46 | 15 | Fylde Vandals (4th XV) |
| Saturday, 15 October 2022 |
| Burnley 2nd XV | 19 | 8 | Colne & Nelson 2nd XV |
| Preston Grasshoppers 4th XV | 36 | 12 | Garstang RFC 3rd XV Men |
| Vale of Lune 3rd XV | 22 | 12 | Fleetwood Wyresiders (2nd XV) |
| Saturday, 22 October 2022 |
| Clitheroe 2nd XV | 45 | 14 | Burnley 2nd XV |
| Fleetwood Wyresiders (2nd XV) | 24 | 47 | Garstang Blues (2nd XV) |
| Fylde Vandals (4th XV) | 19 | 24 | Preston Grasshoppers 4th XV |
| Garstang RFC 3rd XV Men | 5 | 55 | Vale of Lune 3rd XV |
| Preston Grasshoppers 5th XV | 26 | 17 | Colne & Nelson 2nd XV |
| Saturday, 29 October 2022 |
| Burnley 2nd XV | Home Walkover | Fleetwood Wyresiders (2nd XV) |
| Garstang Blues (2nd XV) | 41 | 14 | Garstang RFC 3rd XV Men |
| Preston Grasshoppers 4th XV | 5 | 25 | Vale of Lune 3rd XV |
| Preston Grasshoppers 5th XV | 19 | 45 | Clitheroe 2nd XV |
| Saturday, 5 November 2022 |
| Burnley 2nd XV | 15 | 29 | Garstang RFC 3rd XV Men |
| Colne & Nelson 2nd XV | 26 | 5 | Fylde Vandals (4th XV) |
| Fleetwood Wyresiders (2nd XV) | 37 | 36 | Preston Grasshoppers 5th XV |
| Vale of Lune 3rd XV | 0 | 18 | Garstang Blues (2nd XV) |
| Saturday, 12 November 2022 |
| Fylde Vandals (4th XV) | 17 | 0 | Clitheroe 2nd XV |
| Preston Grasshoppers 4th XV | 14 | 34 | Garstang Blues (2nd XV) |
| Preston Grasshoppers 5th XV | 31 | 62 | Garstang RFC 3rd XV Men |
| Vale of Lune 3rd XV | 65 | 14 | Burnley 2nd XV |
| Saturday, 19 November 2022 |
| Clitheroe 2nd XV | 17 | 47 | Garstang Blues (2nd XV) |
| Fylde Vandals (4th XV) | 21 | 15 | Preston Grasshoppers 5th XV |
| Vale of Lune 3rd XV | 26 | 12 | Colne & Nelson 2nd XV |
| Saturday, 26 November 2022 |
| Colne & Nelson 2nd XV | 22 | 17 | Preston Grasshoppers 4th XV |
| Fleetwood Wyresiders (2nd XV) | 22 | 32 | Fylde Vandals (4th XV) |
| Garstang Blues (2nd XV) | Home Walkover | Burnley 2nd XV |
| Vale of Lune 3rd XV | Away Walkover | Preston Grasshoppers 5th XV |
| Saturday, 3 December 2022 |
| Clitheroe 2nd XV | 17 | 10 | Preston Grasshoppers 4th XV |
| Colne & Nelson 2nd XV | 38 | 15 | Fleetwood Wyresiders (2nd XV) |
| Fylde Vandals (4th XV) | Home Walkover | Garstang RFC 3rd XV Men |
| Preston Grasshoppers 5th XV | 5 | 47 | Burnley 2nd XV |
| Saturday, 17 December 2022 |
| Clitheroe 2nd XV | 5 | 0 | Garstang RFC 3rd XV Men |
| Colne & Nelson 2nd XV | 0 | 5 | Vale of Lune 3rd XV |
| Monday, 26 December 2022 |
| Preston Grasshoppers 4th XV | 33 | 44 | Preston Grasshoppers 5th XV |
| Saturday, 7 January 2023 |
| Fleetwood Wyresiders (2nd XV) | 5 | 0 | Garstang RFC 3rd XV Men |
| Preston Grasshoppers 5th XV | 12 | 22 | Fylde Vandals (4th XV) |
| Vale of Lune 3rd XV | 48 | 0 | Clitheroe 2nd XV |
| Saturday, 14 January 2023 |
| Colne & Nelson 2nd XV | 22 | 3 | Burnley 2nd XV |
| Fleetwood Wyresiders (2nd XV) | 5 | 5 | Vale of Lune 3rd XV |
| Garstang Blues (2nd XV) | 5 | 0 | Clitheroe 2nd XV |
| Garstang RFC 3rd XV Men | 5 | 5 | Preston Grasshoppers 4th XV |
| Saturday, 21 January 2023 |
| Garstang Blues (2nd XV) | 5 | 0 | Fleetwood Wyresiders (2nd XV) |
| Preston Grasshoppers 4th XV | 5 | 0 | Fylde Vandals (4th XV) |
| Vale of Lune 3rd XV | 5 | 0 | Garstang RFC 3rd XV Men |
| Saturday, 28 January 2023 |
| Burnley 2nd XV | 38 | 21 | Fleetwood Wyresiders (2nd XV) |
| Clitheroe 2nd XV | 55 | 22 | Preston Grasshoppers 5th XV |
| Garstang RFC 3rd XV Men | 7 | 38 | Garstang Blues (2nd XV) |
| Vale of Lune 3rd XV | 35 | 7 | Preston Grasshoppers 4th XV |
| Saturday, 4 February 2023 |
| Burnley 2nd XV | 15 | 12 | Preston Grasshoppers 5th XV |
| Fylde Vandals (4th XV) | 0 | 36 | Vale of Lune 3rd XV |
| Garstang Blues (2nd XV) | 83 | 10 | Colne & Nelson 2nd XV |
| Saturday, 11 February 2023 |
| Fleetwood Wyresiders (2nd XV) | 32 | 32 | Preston Grasshoppers 5th XV |
| Fylde Vandals (4th XV) | 29 | 24 | Colne & Nelson 2nd XV |
| Garstang Blues (2nd XV) | 23 | 5 | Vale of Lune 3rd XV |
| Garstang RFC 3rd XV Men | 22 | 37 | Burnley 2nd XV |
| Saturday, 18 February 2023 |
| Burnley 2nd XV | 10 | 55 | Vale of Lune 3rd XV |
| Clitheroe 2nd XV | Home Walkover | Fylde Vandals (4th XV) |
| Garstang Blues (2nd XV) | 51 | 0 | Preston Grasshoppers 4th XV |
| Garstang RFC 3rd XV Men | 17 | 10 | Preston Grasshoppers 5th XV |
| Saturday, 25 February 2023 |
| Burnley 2nd XV | 38 | 27 | Fylde Vandals (4th XV) |
| Colne & Nelson 2nd XV | Home Walkover | Preston Grasshoppers 5th XV |
| Fleetwood Wyresiders (2nd XV) | 24 | 14 | Preston Grasshoppers 4th XV |
| Saturday, 4 March 2023 |
| Fylde Vandals (4th XV) | 53 | 7 | Fleetwood Wyresiders (2nd XV) |
| Garstang Blues (2nd XV) | 44 | 19 | Burnley 2nd XV |
| Preston Grasshoppers 4th XV | 64 | 19 | Colne & Nelson 2nd XV |
| Preston Grasshoppers 5th XV | 0 | 64 | Vale of Lune 3rd XV |
| Saturday, 11 March 2023 |
| Clitheroe 2nd XV | 41 | 0 | Colne & Nelson 2nd XV |
| Garstang Blues (2nd XV) | 78 | 14 | Preston Grasshoppers 5th XV |
| Saturday, 18 March 2023 |
| Burnley 2nd XV | 0 | 34 | Preston Grasshoppers 4th XV |
| Colne & Nelson 2nd XV | Home Walkover | Garstang RFC 3rd XV Men |
| Fleetwood Wyresiders (2nd XV) | 24 | 43 | Clitheroe 2nd XV |
| Garstang Blues (2nd XV) | 71 | 10 | Fylde Vandals (4th XV) |
| Saturday, 25 March 2023 |
| Burnley 2nd XV | 19 | 22 | Clitheroe 2nd XV |