| Saturday, 23 January 2021 |
| Birkenhead Park 3rd XV | Postponed | Sandbach 3rd XV |
| Lymm Eagles | Postponed | Wirral 3rd XV |
| Macclesfield 3rd XV | Postponed | Wilmslow 2nd XV |
| Northwich 3rd XV | Postponed | Firwood Waterloo 3rd XV |
| Saturday, 30 January 2021 |
| Birkenhead Park 3rd XV | Postponed | Lymm Eagles |
| Sandbach 3rd XV | Postponed | Firwood Waterloo 3rd XV |
| Wilmslow 2nd XV | Postponed | Northwich 3rd XV |
| Wirral 3rd XV | Postponed | Macclesfield 3rd XV |
| Saturday, 6 February 2021 |
| Firwood Waterloo 3rd XV | Postponed | Macclesfield 3rd XV |
| Northwich 3rd XV | Postponed | Sandbach 3rd XV |
| Wilmslow 2nd XV | Postponed | Lymm Eagles |
| Wirral 3rd XV | Postponed | Birkenhead Park 3rd XV |
| Saturday, 13 February 2021 |
| Firwood Waterloo 3rd XV | Postponed | Wilmslow 2nd XV |
| Lymm Eagles | Postponed | Sandbach 3rd XV |
| Macclesfield 3rd XV | Postponed | Birkenhead Park 3rd XV |
| Northwich 3rd XV | Postponed | Wirral 3rd XV |
| Saturday, 20 February 2021 |
| Birkenhead Park 3rd XV | Postponed | Northwich 3rd XV |
| Lymm Eagles | Postponed | Macclesfield 3rd XV |
| Sandbach 3rd XV | Postponed | Wilmslow 2nd XV |
| Wirral 3rd XV | Postponed | Firwood Waterloo 3rd XV |
| Saturday, 27 February 2021 |
| Firwood Waterloo 3rd XV | Postponed | Birkenhead Park 3rd XV |
| Macclesfield 3rd XV | Postponed | Sandbach 3rd XV |
| Northwich 3rd XV | Postponed | Lymm Eagles |
| Wilmslow 2nd XV | Postponed | Wirral 3rd XV |
| Saturday, 6 March 2021 |
| Birkenhead Park 3rd XV | Postponed | Wilmslow 2nd XV |
| Lymm Eagles | Postponed | Firwood Waterloo 3rd XV |
| Macclesfield 3rd XV | Postponed | Northwich 3rd XV |
| Sandbach 3rd XV | Postponed | Wirral 3rd XV |
| Saturday, 13 March 2021 |
| Firwood Waterloo 3rd XV | v | Northwich 3rd XV |
| Sandbach 3rd XV | v | Birkenhead Park 3rd XV |
| Wilmslow 2nd XV | v | Macclesfield 3rd XV |
| Wirral 3rd XV | v | Lymm Eagles |
| Saturday, 27 March 2021 |
| Firwood Waterloo 3rd XV | v | Sandbach 3rd XV |
| Lymm Eagles | v | Birkenhead Park 3rd XV |
| Macclesfield 3rd XV | v | Wirral 3rd XV |
| Northwich 3rd XV | v | Wilmslow 2nd XV |
| Saturday, 10 April 2021 |
| Birkenhead Park 3rd XV | v | Macclesfield 3rd XV |
| Sandbach 3rd XV | v | Lymm Eagles |
| Wilmslow 2nd XV | v | Firwood Waterloo 3rd XV |
| Wirral 3rd XV | v | Northwich 3rd XV |
| Saturday, 17 April 2021 |
| Firwood Waterloo 3rd XV | v | Wirral 3rd XV |
| Macclesfield 3rd XV | v | Lymm Eagles |
| Northwich 3rd XV | v | Birkenhead Park 3rd XV |
| Wilmslow 2nd XV | v | Sandbach 3rd XV |
| Saturday, 24 April 2021 |
| Birkenhead Park 3rd XV | v | Firwood Waterloo 3rd XV |
| Lymm Eagles | v | Northwich 3rd XV |
| Sandbach 3rd XV | v | Macclesfield 3rd XV |
| Wirral 3rd XV | v | Wilmslow 2nd XV |
| Saturday, 8 May 2021 |
| Firwood Waterloo 3rd XV | v | Lymm Eagles |
| Northwich 3rd XV | v | Macclesfield 3rd XV |
| Wilmslow 2nd XV | v | Birkenhead Park 3rd XV |
| Wirral 3rd XV | v | Sandbach 3rd XV |
| Saturday, 15 May 2021 |
| Birkenhead Park 3rd XV | v | Wirral 3rd XV |
| Lymm Eagles | v | Wilmslow 2nd XV |
| Macclesfield 3rd XV | v | Firwood Waterloo 3rd XV |
| Sandbach 3rd XV | v | Northwich 3rd XV |