| Saturday, 2 September 2017 |
| Bowdon 2nd XV | 71 | 7 | Whitchurch 2nd XV |
| Chester 3rd XV | 15 | 15 | Aldwinians 2nd XV |
| Glossop 2nd XV | 32 | 20 | Didsbury Toc H 2nd XV |
| Holmes Chapel | 55 | 7 | Sefton 2nd XV |
| Widnes 2nd XV | 40 | 24 | Capenhurst |
| Winnington Park 2nd XV | 24 | 39 | Altrincham Kersal Cougars (2nd XV) |
| Saturday, 9 September 2017 |
| Altrincham Kersal Cougars (2nd XV) | 27 | 12 | Chester 3rd XV |
| Capenhurst | 40 | 52 | Aldwinians 2nd XV |
| New Brighton 2nd XV | 17 | 10 | Bowdon 2nd XV |
| Whitchurch 2nd XV | 63 | 0 | Winnington Park 2nd XV |
| Widnes 2nd XV | 35 | 15 | Glossop 2nd XV |
| Saturday, 16 September 2017 |
| Aldwinians 2nd XV | 10 | 31 | Altrincham Kersal Cougars (2nd XV) |
| Bowdon 2nd XV | 97 | 0 | Sefton 2nd XV |
| Chester 3rd XV | 52 | 21 | Whitchurch 2nd XV |
| Glossop 2nd XV | 45 | 14 | Capenhurst |
| Holmes Chapel | 31 | 7 | Widnes 2nd XV |
| Winnington Park 2nd XV | 24 | 30 | New Brighton 2nd XV |
| Saturday, 23 September 2017 |
| Capenhurst | 5 | 24 | Altrincham Kersal Cougars (2nd XV) |
| Didsbury Toc H 2nd XV | 12 | 10 | Bowdon 2nd XV |
| Glossop 2nd XV | 36 | 16 | Holmes Chapel |
| New Brighton 2nd XV | 19 | 19 | Chester 3rd XV |
| Sefton 2nd XV | 34 | 38 | Winnington Park 2nd XV |
| Whitchurch 2nd XV | 45 | 17 | Aldwinians 2nd XV |
| Saturday, 30 September 2017 |
| Aldwinians 2nd XV | 28 | 7 | New Brighton 2nd XV |
| Altrincham Kersal Cougars (2nd XV) | 57 | 0 | Whitchurch 2nd XV |
| Bowdon 2nd XV | 12 | 6 | Widnes 2nd XV |
| Chester 3rd XV | 45 | 5 | Sefton 2nd XV |
| Holmes Chapel | 20 | 27 | Capenhurst |
| Winnington Park 2nd XV | 17 | 50 | Didsbury Toc H 2nd XV |
| Saturday, 7 October 2017 |
| Capenhurst | 5 | 19 | Whitchurch 2nd XV |
| Didsbury Toc H 2nd XV | 21 | 7 | Chester 3rd XV |
| Glossop 2nd XV | 50 | 5 | Bowdon 2nd XV |
| New Brighton 2nd XV | 0 | 15 | Altrincham Kersal Cougars (2nd XV) |
| Sefton 2nd XV | 17 | 31 | Aldwinians 2nd XV |
| Widnes 2nd XV | 29 | 0 | Winnington Park 2nd XV |
| Saturday, 21 October 2017 |
| Aldwinians 2nd XV | 25 | 14 | Didsbury Toc H 2nd XV |
| Altrincham Kersal Cougars (2nd XV) | 17 | 12 | Sefton 2nd XV |
| Bowdon 2nd XV | 42 | 7 | Holmes Chapel |
| Chester 3rd XV | 22 | 12 | Widnes 2nd XV |
| Whitchurch 2nd XV | 37 | 7 | New Brighton 2nd XV |
| Winnington Park 2nd XV | 0 | 20 | Glossop 2nd XV |
| Saturday, 28 October 2017 |
| Didsbury Toc H 2nd XV | 5 | 12 | Altrincham Kersal Cougars (2nd XV) |
| Glossop 2nd XV | Home Walkover | Chester 3rd XV |
| Holmes Chapel | 26 | 25 | Winnington Park 2nd XV |
| Sefton 2nd XV | 18 | 12 | Whitchurch 2nd XV |
| Widnes 2nd XV | 5 | 24 | Aldwinians 2nd XV |
| Saturday, 4 November 2017 |
| Aldwinians 2nd XV | 16 | 21 | Glossop 2nd XV |
| Altrincham Kersal Cougars (2nd XV) | 12 | 15 | Widnes 2nd XV |
| Bowdon 2nd XV | 43 | 3 | Capenhurst |
| Chester 3rd XV | 33 | 19 | Holmes Chapel |
| New Brighton 2nd XV | 31 | 14 | Sefton 2nd XV |
| Saturday, 11 November 2017 |
| Bowdon 2nd XV | 50 | 0 | Winnington Park 2nd XV |
| Capenhurst | 22 | 14 | Sefton 2nd XV |
| Didsbury Toc H 2nd XV | Home Walkover | New Brighton 2nd XV |
| Glossop 2nd XV | 29 | 28 | Altrincham Kersal Cougars (2nd XV) |
| Holmes Chapel | 21 | 7 | Aldwinians 2nd XV |
| Widnes 2nd XV | 20 | 7 | Whitchurch 2nd XV |
| Saturday, 18 November 2017 |
| Capenhurst | 29 | 39 | New Brighton 2nd XV |
| Saturday, 25 November 2017 |
| Altrincham Kersal Cougars (2nd XV) | 10 | 21 | Holmes Chapel |
| Whitchurch 2nd XV | 7 | 8 | Glossop 2nd XV |
| Saturday, 2 December 2017 |
| Bowdon 2nd XV | 11 | 22 | Aldwinians 2nd XV |
| Glossop 2nd XV | 56 | 3 | New Brighton 2nd XV |
| Holmes Chapel | 33 | 23 | Whitchurch 2nd XV |
| Widnes 2nd XV | 29 | 15 | Sefton 2nd XV |
| Winnington Park 2nd XV | 14 | 19 | Chester 3rd XV |
| Saturday, 9 December 2017 |
| Altrincham Kersal Cougars (2nd XV) | 5 | 5 | Bowdon 2nd XV |
| New Brighton 2nd XV | 5 | 22 | Holmes Chapel |
| Saturday, 16 December 2017 |
| Bowdon 2nd XV | 14 | 13 | New Brighton 2nd XV |
| Holmes Chapel | 26 | 14 | Didsbury Toc H 2nd XV |
| Saturday, 23 December 2017 |
| Didsbury Toc H 2nd XV | 14 | 26 | Holmes Chapel |
| New Brighton 2nd XV | 18 | 29 | Widnes 2nd XV |
| Winnington Park 2nd XV | 52 | 45 | Capenhurst |
| Saturday, 6 January 2018 |
| Altrincham Kersal Cougars (2nd XV) | 21 | 30 | Aldwinians 2nd XV |
| New Brighton 2nd XV | 17 | 26 | Winnington Park 2nd XV |
| Sefton 2nd XV | 0 | 82 | Bowdon 2nd XV |
| Whitchurch 2nd XV | 46 | 7 | Chester 3rd XV |
| Widnes 2nd XV | 27 | 24 | Holmes Chapel |
| Saturday, 13 January 2018 |
| Aldwinians 2nd XV | 57 | 12 | Whitchurch 2nd XV |
| Altrincham Kersal Cougars (2nd XV) | 46 | 7 | Capenhurst |
| Bowdon 2nd XV | 24 | 18 | Didsbury Toc H 2nd XV |
| Chester 3rd XV | 67 | 7 | New Brighton 2nd XV |
| Holmes Chapel | 3 | 27 | Glossop 2nd XV |
| Winnington Park 2nd XV | 34 | 15 | Sefton 2nd XV |
| Saturday, 20 January 2018 |
| Capenhurst | 17 | 22 | Holmes Chapel |
| Didsbury Toc H 2nd XV | 24 | 14 | Winnington Park 2nd XV |
| Sefton 2nd XV | 8 | 36 | Chester 3rd XV |
| Whitchurch 2nd XV | 27 | 25 | Altrincham Kersal Cougars (2nd XV) |
| Saturday, 27 January 2018 |
| Aldwinians 2nd XV | 52 | 10 | Sefton 2nd XV |
| Altrincham Kersal Cougars (2nd XV) | 69 | 5 | New Brighton 2nd XV |
| Bowdon 2nd XV | 15 | 9 | Glossop 2nd XV |
| Chester 3rd XV | 29 | 26 | Didsbury Toc H 2nd XV |
| Whitchurch 2nd XV | Home Walkover | Capenhurst |
| Winnington Park 2nd XV | 46 | 7 | Widnes 2nd XV |
| Saturday, 3 February 2018 |
| New Brighton 2nd XV | 7 | 17 | Whitchurch 2nd XV |
| Sefton 2nd XV | 6 | 46 | Altrincham Kersal Cougars (2nd XV) |
| Saturday, 10 February 2018 |
| Bowdon 2nd XV | 12 | 10 | Chester 3rd XV |
| Sefton 2nd XV | 24 | 28 | Glossop 2nd XV |
| Saturday, 17 February 2018 |
| Aldwinians 2nd XV | 78 | 0 | Widnes 2nd XV |
| Altrincham Kersal Cougars (2nd XV) | 36 | 12 | Didsbury Toc H 2nd XV |
| New Brighton 2nd XV | 12 | 28 | Capenhurst |
| Whitchurch 2nd XV | 60 | 10 | Sefton 2nd XV |
| Winnington Park 2nd XV | 21 | 27 | Holmes Chapel |
| Saturday, 24 February 2018 |
| Aldwinians 2nd XV | 35 | 14 | Capenhurst |
| Glossop 2nd XV | 53 | 0 | Widnes 2nd XV |
| Sefton 2nd XV | 78 | 0 | Didsbury Toc H 2nd XV |
| Winnington Park 2nd XV | 0 | 38 | Whitchurch 2nd XV |
| Saturday, 3 March 2018 |
| Capenhurst | 0 | 5 | Bowdon 2nd XV |
| Didsbury Toc H 2nd XV | 5 | 5 | Whitchurch 2nd XV |
| Didsbury Toc H 2nd XV | 5 | 5 | Whitchurch 2nd XV |
| Glossop 2nd XV | 5 | 5 | Aldwinians 2nd XV |
| Holmes Chapel | 5 | 5 | Chester 3rd XV |
| Widnes 2nd XV | 0 | 5 | Altrincham Kersal Cougars (2nd XV) |
| Saturday, 10 March 2018 |
| Aldwinians 2nd XV | 7 | 13 | Holmes Chapel |
| Didsbury Toc H 2nd XV | 5 | 5 | New Brighton 2nd XV |
| Glossop 2nd XV | 5 | 0 | Chester 3rd XV |
| Sefton 2nd XV | Home Walkover | Capenhurst |
| Whitchurch 2nd XV | 14 | 14 | Widnes 2nd XV |
| Winnington Park 2nd XV | 0 | 5 | Bowdon 2nd XV |
| Saturday, 17 March 2018 |
| Chester 3rd XV | 25 | 13 | Capenhurst |
| Glossop 2nd XV | 10 | 12 | Winnington Park 2nd XV |
| Sefton 2nd XV | 24 | 5 | New Brighton 2nd XV |
| Widnes 2nd XV | 59 | 10 | Bowdon 2nd XV |
| Saturday, 24 March 2018 |
| Aldwinians 2nd XV | 59 | 21 | Winnington Park 2nd XV |
| Chester 3rd XV | 29 | 19 | Bowdon 2nd XV |
| Didsbury Toc H 2nd XV | 76 | 3 | Sefton 2nd XV |
| Glossop 2nd XV | 32 | 0 | Whitchurch 2nd XV |
| Holmes Chapel | 9 | 39 | Altrincham Kersal Cougars (2nd XV) |
| Widnes 2nd XV | 40 | 3 | New Brighton 2nd XV |
| Saturday, 31 March 2018 |
| Capenhurst | 0 | 5 | Glossop 2nd XV |
| Chester 3rd XV | 5 | 18 | Altrincham Kersal Cougars (2nd XV) |
| Didsbury Toc H 2nd XV | 46 | 22 | Widnes 2nd XV |
| Holmes Chapel | 10 | 0 | Bowdon 2nd XV |
| New Brighton 2nd XV | 22 | 20 | Aldwinians 2nd XV |
| Saturday, 7 April 2018 |
| Aldwinians 2nd XV | 35 | 19 | Bowdon 2nd XV |
| Capenhurst | 24 | 43 | Didsbury Toc H 2nd XV |
| Chester 3rd XV | 76 | 0 | Winnington Park 2nd XV |
| Didsbury Toc H 2nd XV | 43 | 24 | Capenhurst |
| New Brighton 2nd XV | 0 | 5 | Glossop 2nd XV |
| Sefton 2nd XV | 31 | 12 | Widnes 2nd XV |
| Whitchurch 2nd XV | 27 | 27 | Holmes Chapel |
| Saturday, 14 April 2018 |
| Bowdon 2nd XV | 15 | 21 | Altrincham Kersal Cougars (2nd XV) |
| Capenhurst | 30 | 32 | Chester 3rd XV |
| Glossop 2nd XV | Home Walkover | Sefton 2nd XV |
| Holmes Chapel | 78 | 0 | New Brighton 2nd XV |
| Widnes 2nd XV | 36 | 19 | Didsbury Toc H 2nd XV |
| Winnington Park 2nd XV | 28 | 52 | Aldwinians 2nd XV |
| Saturday, 21 April 2018 |
| Aldwinians 2nd XV | 26 | 17 | Chester 3rd XV |
| Altrincham Kersal Cougars (2nd XV) | 66 | 7 | Winnington Park 2nd XV |
| Capenhurst | 37 | 48 | Widnes 2nd XV |
| Didsbury Toc H 2nd XV | 32 | 20 | Glossop 2nd XV |
| Sefton 2nd XV | 29 | 34 | Holmes Chapel |
| Whitchurch 2nd XV | 35 | 24 | Bowdon 2nd XV |
| Saturday, 28 April 2018 |
| Altrincham Kersal Cougars (2nd XV) | 46 | 16 | Glossop 2nd XV |
| Capenhurst | Away Walkover | Winnington Park 2nd XV |
| Didsbury Toc H 2nd XV | 26 | 24 | Aldwinians 2nd XV |
| Widnes 2nd XV | 0 | 52 | Chester 3rd XV |