| Saturday, 2 September 2017 |
| Lymm 2nd XV | 43 | 7 | Stockport 2nd XV |
| Macclesfield 3rd XV | 24 | 53 | Vale of Lune 2nd XV |
| Rossendale 2nd XV | 44 | 7 | Rochdale 2nd XV |
| Wilmslow 2nd XV | 49 | 12 | Wirral 2nd XV |
| Saturday, 9 September 2017 |
| Preston Grasshoppers 3rd XV | Home Walkover | Rossendale 2nd XV |
| Rochdale 2nd XV | 19 | 0 | Macclesfield 3rd XV |
| Vale of Lune 2nd XV | Home Walkover | Wilmslow 2nd XV |
| Wirral 2nd XV | 26 | 54 | Lymm 2nd XV |
| Saturday, 16 September 2017 |
| Lymm 2nd XV | 32 | 26 | Vale of Lune 2nd XV |
| Macclesfield 3rd XV | 30 | 32 | Preston Grasshoppers 3rd XV |
| Stockport 2nd XV | 7 | 31 | Wirral 2nd XV |
| Wilmslow 2nd XV | 59 | 14 | Rochdale 2nd XV |
| Saturday, 23 September 2017 |
| Macclesfield 3rd XV | 10 | 44 | Rossendale 2nd XV |
| Preston Grasshoppers 3rd XV | 0 | 55 | Wilmslow 2nd XV |
| Rochdale 2nd XV | 5 | 14 | Lymm 2nd XV |
| Vale of Lune 2nd XV | 48 | 0 | Stockport 2nd XV |
| Saturday, 30 September 2017 |
| Lymm 2nd XV | 71 | 0 | Preston Grasshoppers 3rd XV |
| Stockport 2nd XV | 27 | 17 | Rochdale 2nd XV |
| Wilmslow 2nd XV | 40 | 5 | Rossendale 2nd XV |
| Wirral 2nd XV | 10 | 32 | Vale of Lune 2nd XV |
| Saturday, 7 October 2017 |
| Macclesfield 3rd XV | 15 | 35 | Wilmslow 2nd XV |
| Preston Grasshoppers 3rd XV | 12 | 22 | Stockport 2nd XV |
| Rochdale 2nd XV | 21 | 34 | Wirral 2nd XV |
| Rossendale 2nd XV | 0 | 19 | Lymm 2nd XV |
| Saturday, 21 October 2017 |
| Lymm 2nd XV | 77 | 14 | Macclesfield 3rd XV |
| Stockport 2nd XV | 17 | 32 | Rossendale 2nd XV |
| Vale of Lune 2nd XV | 58 | 21 | Rochdale 2nd XV |
| Wirral 2nd XV | 47 | 0 | Preston Grasshoppers 3rd XV |
| Saturday, 28 October 2017 |
| Macclesfield 3rd XV | 19 | 12 | Stockport 2nd XV |
| Preston Grasshoppers 3rd XV | 0 | 47 | Vale of Lune 2nd XV |
| Rossendale 2nd XV | 5 | 19 | Wirral 2nd XV |
| Wilmslow 2nd XV | 5 | 27 | Lymm 2nd XV |
| Saturday, 4 November 2017 |
| Rochdale 2nd XV | 14 | 15 | Preston Grasshoppers 3rd XV |
| Vale of Lune 2nd XV | 74 | 6 | Rossendale 2nd XV |
| Wilmslow 2nd XV | 16 | 13 | Stockport 2nd XV |
| Wirral 2nd XV | 45 | 12 | Macclesfield 3rd XV |
| Saturday, 11 November 2017 |
| Lymm 2nd XV | 27 | 23 | Wirral 2nd XV |
| Macclesfield 3rd XV | 22 | 5 | Rochdale 2nd XV |
| Rossendale 2nd XV | 20 | 17 | Preston Grasshoppers 3rd XV |
| Wilmslow 2nd XV | 10 | 37 | Vale of Lune 2nd XV |
| Saturday, 18 November 2017 |
| Preston Grasshoppers 3rd XV | 24 | 24 | Macclesfield 3rd XV |
| Rochdale 2nd XV | 32 | 30 | Wilmslow 2nd XV |
| Vale of Lune 2nd XV | 32 | 27 | Lymm 2nd XV |
| Wirral 2nd XV | 34 | 21 | Stockport 2nd XV |
| Saturday, 25 November 2017 |
| Lymm 2nd XV | 52 | 15 | Rochdale 2nd XV |
| Wilmslow 2nd XV | 44 | 0 | Preston Grasshoppers 3rd XV |
| Saturday, 2 December 2017 |
| Preston Grasshoppers 3rd XV | 15 | 55 | Lymm 2nd XV |
| Rochdale 2nd XV | 50 | 17 | Stockport 2nd XV |
| Rossendale 2nd XV | 22 | 13 | Wilmslow 2nd XV |
| Vale of Lune 2nd XV | 27 | 12 | Wirral 2nd XV |
| Saturday, 16 December 2017 |
| Preston Grasshoppers 3rd XV | 28 | 43 | Wirral 2nd XV |
| Saturday, 23 December 2017 |
| Rossendale 2nd XV | 24 | 12 | Macclesfield 3rd XV |
| Saturday, 6 January 2018 |
| Lymm 2nd XV | 26 | 13 | Wilmslow 2nd XV |
| Stockport 2nd XV | 47 | 22 | Macclesfield 3rd XV |
| Vale of Lune 2nd XV | 88 | 0 | Preston Grasshoppers 3rd XV |
| Wirral 2nd XV | 59 | 12 | Rossendale 2nd XV |
| Saturday, 13 January 2018 |
| Macclesfield 3rd XV | 12 | 50 | Wirral 2nd XV |
| Preston Grasshoppers 3rd XV | 7 | 36 | Rochdale 2nd XV |
| Rossendale 2nd XV | 26 | 25 | Vale of Lune 2nd XV |
| Stockport 2nd XV | 31 | 35 | Wilmslow 2nd XV |
| Saturday, 20 January 2018 |
| Rochdale 2nd XV | 12 | 28 | Rossendale 2nd XV |
| Stockport 2nd XV | 7 | 53 | Lymm 2nd XV |
| Vale of Lune 2nd XV | Home Walkover | Macclesfield 3rd XV |
| Wirral 2nd XV | 37 | 5 | Wilmslow 2nd XV |
| Saturday, 27 January 2018 |
| Macclesfield 3rd XV | 31 | 12 | Rochdale 2nd XV |
| Preston Grasshoppers 3rd XV | 5 | 10 | Rossendale 2nd XV |
| Vale of Lune 2nd XV | 42 | 14 | Wilmslow 2nd XV |
| Saturday, 3 February 2018 |
| Preston Grasshoppers 3rd XV | 8 | 55 | Macclesfield 3rd XV |
| Vale of Lune 2nd XV | 7 | 22 | Lymm 2nd XV |
| Wirral 2nd XV | 85 | 0 | Stockport 2nd XV |
| Saturday, 17 February 2018 |
| Lymm 2nd XV | 74 | 5 | Rochdale 2nd XV |
| Macclesfield 3rd XV | 36 | 12 | Rossendale 2nd XV |
| Stockport 2nd XV | 0 | 5 | Vale of Lune 2nd XV |
| Saturday, 24 February 2018 |
| Stockport 2nd XV | 5 | 45 | Preston Grasshoppers 3rd XV |
| Wilmslow 2nd XV | 26 | 38 | Macclesfield 3rd XV |
| Wirral 2nd XV | 54 | 5 | Rochdale 2nd XV |
| Saturday, 3 March 2018 |
| Preston Grasshoppers 3rd XV | 10 | 30 | Lymm 2nd XV |
| Rossendale 2nd XV | 5 | 0 | Wilmslow 2nd XV |
| Saturday, 10 March 2018 |
| Stockport 2nd XV | 48 | 14 | Preston Grasshoppers 3rd XV |
| Wilmslow 2nd XV | 10 | 29 | Macclesfield 3rd XV |
| Wirral 2nd XV | 40 | 5 | Rochdale 2nd XV |
| Saturday, 17 March 2018 |
| Lymm 2nd XV | Home Walkover | Wirral 2nd XV |
| Rossendale 2nd XV | 0 | 34 | Stockport 2nd XV |
| Saturday, 24 March 2018 |
| Macclesfield 3rd XV | 12 | 62 | Lymm 2nd XV |
| Preston Grasshoppers 3rd XV | 31 | 52 | Wirral 2nd XV |
| Rochdale 2nd XV | 5 | 52 | Vale of Lune 2nd XV |
| Rochdale 2nd XV | 5 | 52 | Vale of Lune 2nd XV |
| Rossendale 2nd XV | 11 | 5 | Stockport 2nd XV |
| Saturday, 31 March 2018 |
| Macclesfield 3rd XV | 14 | 46 | Lymm 2nd XV |
| Rochdale 2nd XV | 52 | 14 | Stockport 2nd XV |
| Vale of Lune 2nd XV | 52 | 7 | Wirral 2nd XV |
| Wilmslow 2nd XV | 67 | 5 | Preston Grasshoppers 3rd XV |
| Saturday, 7 April 2018 |
| Lymm 2nd XV | 37 | 11 | Wilmslow 2nd XV |
| Stockport 2nd XV | 19 | 50 | Macclesfield 3rd XV |
| Vale of Lune 2nd XV | 86 | 0 | Preston Grasshoppers 3rd XV |
| Wirral 2nd XV | 5 | 0 | Rossendale 2nd XV |
| Saturday, 14 April 2018 |
| Macclesfield 3rd XV | 48 | 31 | Wirral 2nd XV |
| Preston Grasshoppers 3rd XV | 0 | 73 | Rochdale 2nd XV |
| Rossendale 2nd XV | 15 | 33 | Vale of Lune 2nd XV |
| Wilmslow 2nd XV | 59 | 21 | Stockport 2nd XV |
| Saturday, 21 April 2018 |
| Rochdale 2nd XV | 48 | 13 | Rossendale 2nd XV |
| Stockport 2nd XV | 14 | 71 | Lymm 2nd XV |
| Vale of Lune 2nd XV | 43 | 25 | Macclesfield 3rd XV |
| Wirral 2nd XV | 24 | 17 | Wilmslow 2nd XV |
| Saturday, 28 April 2018 |
| Lymm 2nd XV | 75 | 22 | Rossendale 2nd XV |
| Lymm 2nd XV | 75 | 22 | Rossendale 2nd XV |
| Rochdale 2nd XV | 72 | 0 | Wilmslow 2nd XV |
| Stockport 2nd XV | 57 | 24 | Vale of Lune 2nd XV |