| Saturday, 3 September 2022 |
| Ashton-Under-Lyne 2nd XV | v | Village Spartans |
| Congleton 2nd XV | v | Broughton Park 3rd XV |
| Didsbury Toc H 3rd XV | v | Glossop 3rd XV |
| Knutsford 2nd XV | v | Old Bedians 2nd XV |
| Stockport 3rd XV | v | Buxton |
| Trafford MV 2nd XV | v | Marple 2nd XV |
| Saturday, 10 September 2022 |
| Broughton Park 3rd XV | v | Ashton-Under-Lyne 2nd XV |
| Buxton | v | Old Bedians 2nd XV |
| Glossop 3rd XV | v | Trafford MV 2nd XV |
| Marple 2nd XV | v | Knutsford 2nd XV |
| Stockport 3rd XV | v | Congleton 2nd XV |
| Village Spartans | v | Didsbury Toc H 3rd XV |
| Saturday, 17 September 2022 |
| Ashton-Under-Lyne 2nd XV | v | Stockport 3rd XV |
| Congleton 2nd XV | v | Buxton |
| Didsbury Toc H 3rd XV | v | Broughton Park 3rd XV |
| Knutsford 2nd XV | v | Glossop 3rd XV |
| Old Bedians 2nd XV | v | Marple 2nd XV |
| Trafford MV 2nd XV | v | Village Spartans |
| Saturday, 24 September 2022 |
| Broughton Park 3rd XV | v | Trafford MV 2nd XV |
| Buxton | v | Marple 2nd XV |
| Congleton 2nd XV | v | Ashton-Under-Lyne 2nd XV |
| Glossop 3rd XV | v | Old Bedians 2nd XV |
| Stockport 3rd XV | v | Didsbury Toc H 3rd XV |
| Village Spartans | v | Knutsford 2nd XV |
| Saturday, 1 October 2022 |
| Ashton-Under-Lyne 2nd XV | v | Buxton |
| Didsbury Toc H 3rd XV | v | Congleton 2nd XV |
| Knutsford 2nd XV | v | Broughton Park 3rd XV |
| Marple 2nd XV | v | Glossop 3rd XV |
| Old Bedians 2nd XV | v | Village Spartans |
| Trafford MV 2nd XV | v | Stockport 3rd XV |
| Saturday, 15 October 2022 |
| Ashton-Under-Lyne 2nd XV | v | Didsbury Toc H 3rd XV |
| Broughton Park 3rd XV | v | Old Bedians 2nd XV |
| Buxton | v | Glossop 3rd XV |
| Congleton 2nd XV | v | Trafford MV 2nd XV |
| Stockport 3rd XV | v | Knutsford 2nd XV |
| Village Spartans | v | Marple 2nd XV |
| Saturday, 22 October 2022 |
| Didsbury Toc H 3rd XV | v | Buxton |
| Glossop 3rd XV | v | Village Spartans |
| Knutsford 2nd XV | v | Congleton 2nd XV |
| Marple 2nd XV | v | Broughton Park 3rd XV |
| Stockport 3rd XV | v | Old Bedians 2nd XV |
| Trafford MV 2nd XV | v | Ashton-Under-Lyne 2nd XV |
| Saturday, 29 October 2022 |
| Ashton-Under-Lyne 2nd XV | v | Knutsford 2nd XV |
| Broughton Park 3rd XV | v | Glossop 3rd XV |
| Buxton | v | Village Spartans |
| Congleton 2nd XV | v | Old Bedians 2nd XV |
| Didsbury Toc H 3rd XV | v | Trafford MV 2nd XV |
| Stockport 3rd XV | v | Marple 2nd XV |
| Saturday, 5 November 2022 |
| Ashton-Under-Lyne 2nd XV | v | Old Bedians 2nd XV |
| Glossop 3rd XV | v | Stockport 3rd XV |
| Knutsford 2nd XV | v | Didsbury Toc H 3rd XV |
| Marple 2nd XV | v | Congleton 2nd XV |
| Trafford MV 2nd XV | v | Buxton |
| Village Spartans | v | Broughton Park 3rd XV |
| Saturday, 12 November 2022 |
| Ashton-Under-Lyne 2nd XV | v | Marple 2nd XV |
| Buxton | v | Broughton Park 3rd XV |
| Congleton 2nd XV | v | Glossop 3rd XV |
| Old Bedians 2nd XV | v | Didsbury Toc H 3rd XV |
| Stockport 3rd XV | v | Village Spartans |
| Trafford MV 2nd XV | v | Knutsford 2nd XV |
| Saturday, 26 November 2022 |
| Broughton Park 3rd XV | v | Stockport 3rd XV |
| Glossop 3rd XV | v | Ashton-Under-Lyne 2nd XV |
| Knutsford 2nd XV | v | Buxton |
| Marple 2nd XV | v | Didsbury Toc H 3rd XV |
| Old Bedians 2nd XV | v | Trafford MV 2nd XV |
| Village Spartans | v | Congleton 2nd XV |
| Saturday, 3 December 2022 |
| Ashton-Under-Lyne 2nd XV | v | Broughton Park 3rd XV |
| Congleton 2nd XV | v | Stockport 3rd XV |
| Didsbury Toc H 3rd XV | v | Village Spartans |
| Knutsford 2nd XV | v | Marple 2nd XV |
| Old Bedians 2nd XV | v | Buxton |
| Trafford MV 2nd XV | v | Glossop 3rd XV |
| Saturday, 10 December 2022 |
| Broughton Park 3rd XV | v | Didsbury Toc H 3rd XV |
| Buxton | v | Congleton 2nd XV |
| Glossop 3rd XV | v | Knutsford 2nd XV |
| Marple 2nd XV | v | Old Bedians 2nd XV |
| Stockport 3rd XV | v | Ashton-Under-Lyne 2nd XV |
| Village Spartans | v | Trafford MV 2nd XV |
| Saturday, 17 December 2022 |
| Ashton-Under-Lyne 2nd XV | v | Congleton 2nd XV |
| Didsbury Toc H 3rd XV | v | Stockport 3rd XV |
| Knutsford 2nd XV | v | Village Spartans |
| Marple 2nd XV | v | Buxton |
| Old Bedians 2nd XV | v | Glossop 3rd XV |
| Trafford MV 2nd XV | v | Broughton Park 3rd XV |
| Saturday, 7 January 2023 |
| Broughton Park 3rd XV | v | Knutsford 2nd XV |
| Buxton | v | Ashton-Under-Lyne 2nd XV |
| Congleton 2nd XV | v | Didsbury Toc H 3rd XV |
| Glossop 3rd XV | v | Marple 2nd XV |
| Stockport 3rd XV | v | Trafford MV 2nd XV |
| Village Spartans | v | Old Bedians 2nd XV |
| Saturday, 14 January 2023 |
| Didsbury Toc H 3rd XV | v | Ashton-Under-Lyne 2nd XV |
| Glossop 3rd XV | v | Buxton |
| Knutsford 2nd XV | v | Stockport 3rd XV |
| Marple 2nd XV | v | Village Spartans |
| Old Bedians 2nd XV | v | Broughton Park 3rd XV |
| Trafford MV 2nd XV | v | Congleton 2nd XV |
| Saturday, 21 January 2023 |
| Ashton-Under-Lyne 2nd XV | v | Trafford MV 2nd XV |
| Broughton Park 3rd XV | v | Marple 2nd XV |
| Buxton | v | Didsbury Toc H 3rd XV |
| Congleton 2nd XV | v | Knutsford 2nd XV |
| Old Bedians 2nd XV | v | Stockport 3rd XV |
| Village Spartans | v | Glossop 3rd XV |
| Saturday, 28 January 2023 |
| Glossop 3rd XV | v | Broughton Park 3rd XV |
| Knutsford 2nd XV | v | Ashton-Under-Lyne 2nd XV |
| Marple 2nd XV | v | Stockport 3rd XV |
| Old Bedians 2nd XV | v | Congleton 2nd XV |
| Trafford MV 2nd XV | v | Didsbury Toc H 3rd XV |
| Village Spartans | v | Buxton |
| Saturday, 11 February 2023 |
| Broughton Park 3rd XV | v | Village Spartans |
| Buxton | v | Trafford MV 2nd XV |
| Congleton 2nd XV | v | Marple 2nd XV |
| Didsbury Toc H 3rd XV | v | Knutsford 2nd XV |
| Old Bedians 2nd XV | v | Ashton-Under-Lyne 2nd XV |
| Stockport 3rd XV | v | Glossop 3rd XV |
| Saturday, 18 February 2023 |
| Broughton Park 3rd XV | v | Buxton |
| Didsbury Toc H 3rd XV | v | Old Bedians 2nd XV |
| Glossop 3rd XV | v | Congleton 2nd XV |
| Knutsford 2nd XV | v | Trafford MV 2nd XV |
| Marple 2nd XV | v | Ashton-Under-Lyne 2nd XV |
| Village Spartans | v | Stockport 3rd XV |
| Saturday, 4 March 2023 |
| Ashton-Under-Lyne 2nd XV | v | Glossop 3rd XV |
| Buxton | v | Knutsford 2nd XV |
| Congleton 2nd XV | v | Village Spartans |
| Didsbury Toc H 3rd XV | v | Marple 2nd XV |
| Stockport 3rd XV | v | Broughton Park 3rd XV |
| Trafford MV 2nd XV | v | Old Bedians 2nd XV |
| Saturday, 11 March 2023 |
| Broughton Park 3rd XV | v | Congleton 2nd XV |
| Buxton | v | Stockport 3rd XV |
| Glossop 3rd XV | v | Didsbury Toc H 3rd XV |
| Marple 2nd XV | v | Trafford MV 2nd XV |
| Old Bedians 2nd XV | v | Knutsford 2nd XV |
| Village Spartans | v | Ashton-Under-Lyne 2nd XV |