| Saturday, 6 September 2025 |
| Birkenhead Park 3rd XV | 22 | 52 | Widnes 3rd XV |
| Hoylake 2nd XV | 78 | 0 | Oxton Parkonians 2nd XV |
| Merseyside Police | 17 | 31 | Sefton 3rd XV |
| Saturday, 13 September 2025 |
| Capenhurst RUFC 2nd XV Men | 55 | 33 | Moore 2nd XV |
| New Brighton 3rd XV | 99 | 5 | Birkenhead Park 3rd XV |
| Northwich 3rd XV | Postponed | Hoylake 2nd XV |
| Oxton Parkonians 2nd XV | 26 | 40 | Merseyside Police |
| Sefton 3rd XV | 10 | 38 | Widnes 3rd XV |
| Saturday, 20 September 2025 |
| Port Sunlight 2nd XV | 12 | 70 | New Brighton 3rd XV |
| Saturday, 4 October 2025 |
| Birkenhead Park 3rd XV | 36 | 22 | Sefton 3rd XV |
| Hoylake 2nd XV | Away Walkover | Capenhurst RUFC 2nd XV Men |
| Merseyside Police | 24 | 7 | Northwich 3rd XV |
| Moore 2nd XV | 0 | 82 | New Brighton 3rd XV |
| Widnes 3rd XV | 54 | 24 | Oxton Parkonians 2nd XV |
| Saturday, 11 October 2025 |
| Capenhurst RUFC 2nd XV Men | 75 | 19 | Merseyside Police |
| New Brighton 3rd XV | 50 | 26 | Hoylake 2nd XV |
| Northwich 3rd XV | 33 | 45 | Widnes 3rd XV |
| Oxton Parkonians 2nd XV | 45 | 39 | Sefton 3rd XV |
| Wallasey 2nd XV | Away Walkover | Birkenhead Park 3rd XV |
| Saturday, 18 October 2025 |
| Birkenhead Park 3rd XV | 14 | 81 | Oxton Parkonians 2nd XV |
| Hoylake 2nd XV | Away Walkover | Port Sunlight 2nd XV |
| Merseyside Police | Away Walkover | New Brighton 3rd XV |
| Widnes 3rd XV | 34 | 29 | Capenhurst RUFC 2nd XV Men |
| Saturday, 25 October 2025 |
| Port Sunlight 2nd XV | 36 | 58 | Birkenhead Park 3rd XV |
| Sefton 3rd XV | Home Walkover | Northwich 3rd XV |
| Saturday, 8 November 2025 |
| Moore 2nd XV | v | Birkenhead Park 3rd XV |
| New Brighton 3rd XV | v | Widnes 3rd XV |
| Northwich 3rd XV | v | Oxton Parkonians 2nd XV |
| Port Sunlight 2nd XV | v | Merseyside Police |
| Sefton 3rd XV | v | Capenhurst RUFC 2nd XV Men |
| Wallasey 2nd XV | v | Hoylake 2nd XV |
| Saturday, 22 November 2025 |
| Birkenhead Park 3rd XV | v | Northwich 3rd XV |
| Hoylake 2nd XV | v | Moore 2nd XV |
| Merseyside Police | v | Wallasey 2nd XV |
| Oxton Parkonians 2nd XV | v | Capenhurst RUFC 2nd XV Men |
| Sefton 3rd XV | v | New Brighton 3rd XV |
| Widnes 3rd XV | v | Port Sunlight 2nd XV |
| Saturday, 29 November 2025 |
| Hoylake 2nd XV | v | Birkenhead Park 3rd XV |
| Moore 2nd XV | v | Merseyside Police |
| New Brighton 3rd XV | v | Oxton Parkonians 2nd XV |
| Northwich 3rd XV | v | Capenhurst RUFC 2nd XV Men |
| Port Sunlight 2nd XV | v | Sefton 3rd XV |
| Wallasey 2nd XV | v | Widnes 3rd XV |
| Saturday, 6 December 2025 |
| Merseyside Police | v | Hoylake 2nd XV |
| Northwich 3rd XV | v | New Brighton 3rd XV |
| Oxton Parkonians 2nd XV | v | Port Sunlight 2nd XV |
| Sefton 3rd XV | v | Wallasey 2nd XV |
| Widnes 3rd XV | v | Moore 2nd XV |
| Saturday, 13 December 2025 |
| Hoylake 2nd XV | v | Widnes 3rd XV |
| Merseyside Police | v | Birkenhead Park 3rd XV |
| Moore 2nd XV | v | Sefton 3rd XV |
| New Brighton 3rd XV | v | Capenhurst RUFC 2nd XV Men |
| Port Sunlight 2nd XV | v | Northwich 3rd XV |
| Wallasey 2nd XV | v | Oxton Parkonians 2nd XV |
| Saturday, 20 December 2025 |
| Birkenhead Park 3rd XV | v | New Brighton 3rd XV |
| Northwich 3rd XV | v | Wallasey 2nd XV |
| Oxton Parkonians 2nd XV | v | Moore 2nd XV |
| Sefton 3rd XV | v | Hoylake 2nd XV |
| Widnes 3rd XV | v | Merseyside Police |
| Saturday, 10 January 2026 |
| Birkenhead Park 3rd XV | v | Port Sunlight 2nd XV |
| Merseyside Police | v | Oxton Parkonians 2nd XV |
| Moore 2nd XV | v | Capenhurst RUFC 2nd XV Men |
| New Brighton 3rd XV | v | Wallasey 2nd XV |
| New Brighton 3rd XV | v | Wallasey 2nd XV |
| Northwich 3rd XV | v | Hoylake 2nd XV |
| Widnes 3rd XV | v | Sefton 3rd XV |
| Saturday, 17 January 2026 |
| Capenhurst RUFC 2nd XV Men | v | Hoylake 2nd XV |
| New Brighton 3rd XV | v | Moore 2nd XV |
| Northwich 3rd XV | v | Merseyside Police |
| Oxton Parkonians 2nd XV | v | Widnes 3rd XV |
| Port Sunlight 2nd XV | v | Wallasey 2nd XV |
| Port Sunlight 2nd XV | v | Wallasey 2nd XV |
| Sefton 3rd XV | v | Birkenhead Park 3rd XV |
| Saturday, 24 January 2026 |
| Birkenhead Park 3rd XV | v | Wallasey 2nd XV |
| Hoylake 2nd XV | v | New Brighton 3rd XV |
| Merseyside Police | v | Capenhurst RUFC 2nd XV Men |
| Moore 2nd XV | v | Port Sunlight 2nd XV |
| Moore 2nd XV | v | Port Sunlight 2nd XV |
| Sefton 3rd XV | v | Oxton Parkonians 2nd XV |
| Widnes 3rd XV | v | Northwich 3rd XV |
| Saturday, 14 February 2026 |
| Capenhurst RUFC 2nd XV Men | v | Widnes 3rd XV |
| Moore 2nd XV | v | Wallasey 2nd XV |
| Moore 2nd XV | v | Wallasey 2nd XV |
| New Brighton 3rd XV | v | Merseyside Police |
| Oxton Parkonians 2nd XV | v | Birkenhead Park 3rd XV |
| Port Sunlight 2nd XV | v | Hoylake 2nd XV |
| Sefton 3rd XV | v | Northwich 3rd XV |
| Saturday, 28 February 2026 |
| Birkenhead Park 3rd XV | v | Moore 2nd XV |
| Capenhurst RUFC 2nd XV Men | v | Sefton 3rd XV |
| Hoylake 2nd XV | v | Wallasey 2nd XV |
| Merseyside Police | v | Port Sunlight 2nd XV |
| Oxton Parkonians 2nd XV | v | Northwich 3rd XV |
| Widnes 3rd XV | v | New Brighton 3rd XV |
| Saturday, 7 March 2026 |
| Capenhurst RUFC 2nd XV Men | v | Oxton Parkonians 2nd XV |
| Moore 2nd XV | v | Hoylake 2nd XV |
| New Brighton 3rd XV | v | Sefton 3rd XV |
| Northwich 3rd XV | v | Birkenhead Park 3rd XV |
| Port Sunlight 2nd XV | v | Widnes 3rd XV |
| Wallasey 2nd XV | v | Merseyside Police |
| Saturday, 21 March 2026 |
| Birkenhead Park 3rd XV | v | Hoylake 2nd XV |
| Capenhurst RUFC 2nd XV Men | v | Northwich 3rd XV |
| Merseyside Police | v | Moore 2nd XV |
| Oxton Parkonians 2nd XV | v | New Brighton 3rd XV |
| Sefton 3rd XV | v | Port Sunlight 2nd XV |
| Widnes 3rd XV | v | Wallasey 2nd XV |
| Saturday, 28 March 2026 |
| Birkenhead Park 3rd XV | v | Capenhurst RUFC 2nd XV Men |
| Birkenhead Park 3rd XV | v | Capenhurst RUFC 2nd XV Men |
| Hoylake 2nd XV | v | Merseyside Police |
| Moore 2nd XV | v | Widnes 3rd XV |
| New Brighton 3rd XV | v | Northwich 3rd XV |
| Port Sunlight 2nd XV | v | Oxton Parkonians 2nd XV |
| Wallasey 2nd XV | v | Sefton 3rd XV |
| Saturday, 11 April 2026 |
| Birkenhead Park 3rd XV | v | Merseyside Police |
| Capenhurst RUFC 2nd XV Men | v | New Brighton 3rd XV |
| Northwich 3rd XV | v | Port Sunlight 2nd XV |
| Oxton Parkonians 2nd XV | v | Wallasey 2nd XV |
| Sefton 3rd XV | v | Moore 2nd XV |
| Widnes 3rd XV | v | Hoylake 2nd XV |
| Saturday, 18 April 2026 |
| Hoylake 2nd XV | v | Sefton 3rd XV |
| Merseyside Police | v | Widnes 3rd XV |
| Moore 2nd XV | v | Oxton Parkonians 2nd XV |
| Port Sunlight 2nd XV | v | Capenhurst RUFC 2nd XV Men |
| Port Sunlight 2nd XV | v | Capenhurst RUFC 2nd XV Men |
| Wallasey 2nd XV | v | Northwich 3rd XV |
| Saturday, 25 April 2026 |
| Capenhurst RUFC 2nd XV Men | v | Wallasey 2nd XV |
| Capenhurst RUFC 2nd XV Men | v | Wallasey 2nd XV |
| Moore 2nd XV | v | Northwich 3rd XV |
| Moore 2nd XV | v | Northwich 3rd XV |
| New Brighton 3rd XV | v | Port Sunlight 2nd XV |
| Oxton Parkonians 2nd XV | v | Hoylake 2nd XV |
| Sefton 3rd XV | v | Merseyside Police |
| Widnes 3rd XV | v | Birkenhead Park 3rd XV |