| Saturday, 6 September 2025 |
| Caldy 3rd XV | 29 | 31 | New Brighton 2nd XV |
| Capenhurst | 19 | 29 | Crosby St Mary's |
| Chester 3rd XV | Away Walkover | Newton-le-Willows |
| Oxton Parkonians | 29 | 7 | Port Sunlight |
| Saturday, 13 September 2025 |
| Caldy 3rd XV | 12 | 34 | Oxton Parkonians |
| New Brighton 2nd XV | 78 | 5 | Chester 3rd XV |
| Newton-le-Willows | 22 | 30 | Capenhurst |
| Saturday, 20 September 2025 |
| Caldy 3rd XV | 10 | 22 | Capenhurst |
| Crosby St Mary's | Home Walkover | Chester 3rd XV |
| Sefton 2nd XV | 7 | 26 | Birchfield |
| Saturday, 4 October 2025 |
| Capenhurst | 20 | 14 | New Brighton 2nd XV |
| Chester 3rd XV | 12 | 27 | Caldy 3rd XV |
| Oxton Parkonians | 34 | 12 | Birchfield |
| Port Sunlight | 38 | 12 | Sefton 2nd XV |
| Saturday, 11 October 2025 |
| Chester 3rd XV | 7 | 84 | Oxton Parkonians |
| Crosby St Mary's | 14 | 46 | Port Sunlight |
| Saturday, 18 October 2025 |
| Birchfield | 56 | 0 | Crosby St Mary's |
| Capenhurst | Home Walkover | Chester 3rd XV |
| Oxton Parkonians | 60 | 7 | Sefton 2nd XV |
| Port Sunlight | 39 | 31 | Newton-le-Willows |
| Saturday, 25 October 2025 |
| Birchfield | 48 | 5 | Port Sunlight |
| Newton-le-Willows | Home Walkover | Crosby St Mary's |
| Saturday, 8 November 2025 |
| Capenhurst | v | Oxton Parkonians |
| Crosby St Mary's | v | Sefton 2nd XV |
| New Brighton 2nd XV | v | Port Sunlight |
| Newton-le-Willows | v | Birchfield |
| Saturday, 22 November 2025 |
| Birchfield | v | New Brighton 2nd XV |
| Oxton Parkonians | v | Crosby St Mary's |
| Port Sunlight | v | Caldy 3rd XV |
| Sefton 2nd XV | v | Newton-le-Willows |
| Saturday, 29 November 2025 |
| Caldy 3rd XV | v | Birchfield |
| Chester 3rd XV | v | Port Sunlight |
| New Brighton 2nd XV | v | Sefton 2nd XV |
| Saturday, 6 December 2025 |
| Birchfield | v | Chester 3rd XV |
| Crosby St Mary's | v | New Brighton 2nd XV |
| Oxton Parkonians | v | Newton-le-Willows |
| Port Sunlight | v | Capenhurst |
| Sefton 2nd XV | v | Caldy 3rd XV |
| Saturday, 13 December 2025 |
| Caldy 3rd XV | v | Crosby St Mary's |
| Capenhurst | v | Birchfield |
| Chester 3rd XV | v | Sefton 2nd XV |
| New Brighton 2nd XV | v | Newton-le-Willows |
| Saturday, 20 December 2025 |
| Newton-le-Willows | v | Caldy 3rd XV |
| Oxton Parkonians | v | New Brighton 2nd XV |
| Sefton 2nd XV | v | Capenhurst |
| Saturday, 10 January 2026 |
| Capenhurst | v | Newton-le-Willows |
| Chester 3rd XV | v | New Brighton 2nd XV |
| Oxton Parkonians | v | Caldy 3rd XV |
| Port Sunlight | v | Birchfield |
| Saturday, 17 January 2026 |
| Birchfield | v | Oxton Parkonians |
| Caldy 3rd XV | v | Chester 3rd XV |
| New Brighton 2nd XV | v | Capenhurst |
| Sefton 2nd XV | v | Port Sunlight |
| Saturday, 24 January 2026 |
| Birchfield | v | Sefton 2nd XV |
| Capenhurst | v | Caldy 3rd XV |
| Oxton Parkonians | v | Chester 3rd XV |
| Port Sunlight | v | Crosby St Mary's |
| Saturday, 14 February 2026 |
| Capenhurst | v | Chester 3rd XV |
| Crosby St Mary's | v | Birchfield |
| Newton-le-Willows | v | Port Sunlight |
| Sefton 2nd XV | v | Oxton Parkonians |
| Saturday, 28 February 2026 |
| Birchfield | v | Newton-le-Willows |
| Oxton Parkonians | v | Capenhurst |
| Port Sunlight | v | New Brighton 2nd XV |
| Sefton 2nd XV | v | Crosby St Mary's |
| Saturday, 7 March 2026 |
| Caldy 3rd XV | v | Port Sunlight |
| Crosby St Mary's | v | Oxton Parkonians |
| New Brighton 2nd XV | v | Birchfield |
| Newton-le-Willows | v | Sefton 2nd XV |
| Saturday, 21 March 2026 |
| Birchfield | v | Caldy 3rd XV |
| Newton-le-Willows | v | Crosby St Mary's |
| Port Sunlight | v | Chester 3rd XV |
| Sefton 2nd XV | v | New Brighton 2nd XV |
| Saturday, 28 March 2026 |
| Caldy 3rd XV | v | Sefton 2nd XV |
| Capenhurst | v | Port Sunlight |
| Chester 3rd XV | v | Birchfield |
| New Brighton 2nd XV | v | Crosby St Mary's |
| Newton-le-Willows | v | Oxton Parkonians |
| Saturday, 11 April 2026 |
| Birchfield | v | Capenhurst |
| Crosby St Mary's | v | Caldy 3rd XV |
| Newton-le-Willows | v | New Brighton 2nd XV |
| Sefton 2nd XV | v | Chester 3rd XV |
| Saturday, 18 April 2026 |
| Caldy 3rd XV | v | Newton-le-Willows |
| Capenhurst | v | Sefton 2nd XV |
| Crosby St Mary's | v | Chester 3rd XV |
| New Brighton 2nd XV | v | Oxton Parkonians |
| Saturday, 25 April 2026 |
| Crosby St Mary's | v | Capenhurst |
| New Brighton 2nd XV | v | Caldy 3rd XV |
| Newton-le-Willows | v | Chester 3rd XV |
| Port Sunlight | v | Oxton Parkonians |