| Saturday, 6 September 2025 |
| Bowdon 2nd XV | 47 | 5 | Wallasey |
| Burnage 2nd XV | 31 | 22 | Crewe & Nantwich 2nd XV |
| Ellesmere Port | 54 | 32 | Firwood Waterloo 2nd XV |
| Holmes Chapel | 15 | 37 | Broughton Park 2nd XV |
| Marple | 17 | 24 | Didsbury Toc H 2nd XV |
| Sandbach 3rd XV | 5 | 60 | Prenton |
| Saturday, 13 September 2025 |
| Broughton Park 2nd XV | 29 | 33 | Marple |
| Burnage 2nd XV | 55 | 22 | Wallasey |
| Didsbury Toc H 2nd XV | 54 | 12 | Sandbach 3rd XV |
| Ellesmere Port | Home Walkover | Holmes Chapel |
| Firwood Waterloo 2nd XV | 35 | 19 | Bowdon 2nd XV |
| Saturday, 4 October 2025 |
| Bowdon 2nd XV | 19 | 22 | Burnage 2nd XV |
| Didsbury Toc H 2nd XV | 43 | 14 | Crewe & Nantwich 2nd XV |
| Holmes Chapel | Home Walkover | Firwood Waterloo 2nd XV |
| Marple | 29 | 29 | Ellesmere Port |
| Sandbach 3rd XV | 17 | 12 | Broughton Park 2nd XV |
| Saturday, 11 October 2025 |
| Broughton Park 2nd XV | 12 | 22 | Crewe & Nantwich 2nd XV |
| Didsbury Toc H 2nd XV | Home Walkover | Wallasey |
| Ellesmere Port | 65 | 19 | Sandbach 3rd XV |
| Holmes Chapel | 13 | 66 | Bowdon 2nd XV |
| Marple | 29 | 29 | Firwood Waterloo 2nd XV |
| Prenton | 97 | 35 | Burnage 2nd XV |
| Saturday, 18 October 2025 |
| Bowdon 2nd XV | 34 | 39 | Prenton |
| Burnage 2nd XV | 43 | 52 | Didsbury Toc H 2nd XV |
| Ellesmere Port | 38 | 10 | Crewe & Nantwich 2nd XV |
| Marple | Home Walkover | Holmes Chapel |
| Sandbach 3rd XV | 60 | 40 | Firwood Waterloo 2nd XV |
| Wallasey | 7 | 27 | Broughton Park 2nd XV |
| Saturday, 25 October 2025 |
| Prenton | 45 | 10 | Crewe & Nantwich 2nd XV |
| Saturday, 8 November 2025 |
| Broughton Park 2nd XV | v | Burnage 2nd XV |
| Didsbury Toc H 2nd XV | v | Prenton |
| Ellesmere Port | v | Wallasey |
| Firwood Waterloo 2nd XV | v | Crewe & Nantwich 2nd XV |
| Holmes Chapel | v | Sandbach 3rd XV |
| Marple | v | Bowdon 2nd XV |
| Saturday, 15 November 2025 |
| Wallasey | v | Prenton |
| Saturday, 22 November 2025 |
| Bowdon 2nd XV | v | Didsbury Toc H 2nd XV |
| Burnage 2nd XV | v | Ellesmere Port |
| Crewe & Nantwich 2nd XV | v | Holmes Chapel |
| Prenton | v | Broughton Park 2nd XV |
| Sandbach 3rd XV | v | Marple |
| Wallasey | v | Firwood Waterloo 2nd XV |
| Saturday, 29 November 2025 |
| Broughton Park 2nd XV | v | Didsbury Toc H 2nd XV |
| Ellesmere Port | v | Prenton |
| Firwood Waterloo 2nd XV | v | Burnage 2nd XV |
| Holmes Chapel | v | Wallasey |
| Marple | v | Crewe & Nantwich 2nd XV |
| Sandbach 3rd XV | v | Bowdon 2nd XV |
| Saturday, 6 December 2025 |
| Bowdon 2nd XV | v | Broughton Park 2nd XV |
| Burnage 2nd XV | v | Holmes Chapel |
| Crewe & Nantwich 2nd XV | v | Sandbach 3rd XV |
| Didsbury Toc H 2nd XV | v | Ellesmere Port |
| Prenton | v | Firwood Waterloo 2nd XV |
| Wallasey | v | Marple |
| Saturday, 13 December 2025 |
| Broughton Park 2nd XV | v | Ellesmere Port |
| Crewe & Nantwich 2nd XV | v | Bowdon 2nd XV |
| Firwood Waterloo 2nd XV | v | Didsbury Toc H 2nd XV |
| Holmes Chapel | v | Prenton |
| Marple | v | Burnage 2nd XV |
| Sandbach 3rd XV | v | Wallasey |
| Saturday, 20 December 2025 |
| Bowdon 2nd XV | v | Ellesmere Port |
| Broughton Park 2nd XV | v | Firwood Waterloo 2nd XV |
| Burnage 2nd XV | v | Sandbach 3rd XV |
| Didsbury Toc H 2nd XV | v | Holmes Chapel |
| Prenton | v | Marple |
| Wallasey | v | Crewe & Nantwich 2nd XV |
| Saturday, 10 January 2026 |
| Bowdon 2nd XV | v | Firwood Waterloo 2nd XV |
| Crewe & Nantwich 2nd XV | v | Prenton |
| Ellesmere Port | v | Holmes Chapel |
| Marple | v | Broughton Park 2nd XV |
| Sandbach 3rd XV | v | Didsbury Toc H 2nd XV |
| Wallasey | v | Burnage 2nd XV |
| Saturday, 17 January 2026 |
| Broughton Park 2nd XV | v | Sandbach 3rd XV |
| Burnage 2nd XV | v | Bowdon 2nd XV |
| Crewe & Nantwich 2nd XV | v | Didsbury Toc H 2nd XV |
| Ellesmere Port | v | Marple |
| Holmes Chapel | v | Firwood Waterloo 2nd XV |
| Prenton | v | Wallasey |
| Saturday, 24 January 2026 |
| Bowdon 2nd XV | v | Holmes Chapel |
| Burnage 2nd XV | v | Prenton |
| Crewe & Nantwich 2nd XV | v | Broughton Park 2nd XV |
| Didsbury Toc H 2nd XV | v | Wallasey |
| Firwood Waterloo 2nd XV | v | Marple |
| Sandbach 3rd XV | v | Ellesmere Port |
| Saturday, 31 January 2026 |
| Firwood Waterloo 2nd XV | v | Sandbach 3rd XV |
| Saturday, 14 February 2026 |
| Broughton Park 2nd XV | v | Wallasey |
| Didsbury Toc H 2nd XV | v | Burnage 2nd XV |
| Ellesmere Port | v | Crewe & Nantwich 2nd XV |
| Marple | v | Holmes Chapel |
| Prenton | v | Bowdon 2nd XV |
| Saturday, 28 February 2026 |
| Bowdon 2nd XV | v | Marple |
| Burnage 2nd XV | v | Broughton Park 2nd XV |
| Crewe & Nantwich 2nd XV | v | Firwood Waterloo 2nd XV |
| Prenton | v | Didsbury Toc H 2nd XV |
| Sandbach 3rd XV | v | Holmes Chapel |
| Wallasey | v | Ellesmere Port |
| Saturday, 7 March 2026 |
| Broughton Park 2nd XV | v | Prenton |
| Didsbury Toc H 2nd XV | v | Bowdon 2nd XV |
| Ellesmere Port | v | Burnage 2nd XV |
| Firwood Waterloo 2nd XV | v | Wallasey |
| Holmes Chapel | v | Crewe & Nantwich 2nd XV |
| Marple | v | Sandbach 3rd XV |
| Saturday, 21 March 2026 |
| Bowdon 2nd XV | v | Sandbach 3rd XV |
| Burnage 2nd XV | v | Firwood Waterloo 2nd XV |
| Crewe & Nantwich 2nd XV | v | Marple |
| Didsbury Toc H 2nd XV | v | Broughton Park 2nd XV |
| Prenton | v | Ellesmere Port |
| Wallasey | v | Holmes Chapel |
| Saturday, 28 March 2026 |
| Broughton Park 2nd XV | v | Bowdon 2nd XV |
| Ellesmere Port | v | Didsbury Toc H 2nd XV |
| Firwood Waterloo 2nd XV | v | Prenton |
| Holmes Chapel | v | Burnage 2nd XV |
| Marple | v | Wallasey |
| Sandbach 3rd XV | v | Crewe & Nantwich 2nd XV |
| Saturday, 11 April 2026 |
| Bowdon 2nd XV | v | Crewe & Nantwich 2nd XV |
| Burnage 2nd XV | v | Marple |
| Didsbury Toc H 2nd XV | v | Firwood Waterloo 2nd XV |
| Ellesmere Port | v | Broughton Park 2nd XV |
| Prenton | v | Holmes Chapel |
| Wallasey | v | Sandbach 3rd XV |
| Saturday, 18 April 2026 |
| Crewe & Nantwich 2nd XV | v | Wallasey |
| Ellesmere Port | v | Bowdon 2nd XV |
| Firwood Waterloo 2nd XV | v | Broughton Park 2nd XV |
| Holmes Chapel | v | Didsbury Toc H 2nd XV |
| Marple | v | Prenton |
| Sandbach 3rd XV | v | Burnage 2nd XV |
| Saturday, 25 April 2026 |
| Broughton Park 2nd XV | v | Holmes Chapel |
| Crewe & Nantwich 2nd XV | v | Burnage 2nd XV |
| Didsbury Toc H 2nd XV | v | Marple |
| Firwood Waterloo 2nd XV | v | Ellesmere Port |
| Prenton | v | Sandbach 3rd XV |
| Wallasey | v | Bowdon 2nd XV |