| Saturday, 7 September 2024 |
| Aspull 3rd XV | 22 | 24 | Village Spartans |
| Congleton 2nd XV | 15 | 29 | Heaton Moor 2nd XV |
| Didsbury Toc H 3rd XV | 17 | 10 | Bury 2nd XV |
| Leigh 3rd XV | 31 | 36 | Broughton |
| Manchester Hawks | 26 | 17 | Eccles RFC 4th XV |
| Marple 2nd XV | 22 | 27 | Wythenshawe |
| Saturday, 14 September 2024 |
| Ashton-Under-Lyne 2nd XV | v | Leigh 3rd XV |
| Broughton | v | Congleton 2nd XV |
| Bury 2nd XV | v | Manchester Hawks |
| Eccles RFC 4th XV | v | Aspull 3rd XV |
| Heaton Moor 2nd XV | v | Marple 2nd XV |
| Wythenshawe | v | Didsbury Toc H 3rd XV |
| Saturday, 21 September 2024 |
| Aspull 3rd XV | v | Bury 2nd XV |
| Congleton 2nd XV | v | Ashton-Under-Lyne 2nd XV |
| Didsbury Toc H 3rd XV | v | Heaton Moor 2nd XV |
| Manchester Hawks | v | Wythenshawe |
| Marple 2nd XV | v | Broughton |
| Village Spartans | v | Eccles RFC 4th XV |
| Saturday, 28 September 2024 |
| Ashton-Under-Lyne 2nd XV | v | Marple 2nd XV |
| Broughton | v | Didsbury Toc H 3rd XV |
| Bury 2nd XV | v | Village Spartans |
| Heaton Moor 2nd XV | v | Manchester Hawks |
| Leigh 3rd XV | v | Congleton 2nd XV |
| Wythenshawe | v | Aspull 3rd XV |
| Saturday, 5 October 2024 |
| Ashton-Under-Lyne 2nd XV | v | Wythenshawe |
| Broughton | v | Heaton Moor 2nd XV |
| Congleton 2nd XV | v | Eccles RFC 4th XV |
| Didsbury Toc H 3rd XV | v | Aspull 3rd XV |
| Leigh 3rd XV | v | Bury 2nd XV |
| Marple 2nd XV | v | Village Spartans |
| Saturday, 12 October 2024 |
| Aspull 3rd XV | v | Heaton Moor 2nd XV |
| Didsbury Toc H 3rd XV | v | Ashton-Under-Lyne 2nd XV |
| Eccles RFC 4th XV | v | Bury 2nd XV |
| Manchester Hawks | v | Broughton |
| Marple 2nd XV | v | Leigh 3rd XV |
| Village Spartans | v | Wythenshawe |
| Saturday, 19 October 2024 |
| Ashton-Under-Lyne 2nd XV | v | Manchester Hawks |
| Broughton | v | Aspull 3rd XV |
| Congleton 2nd XV | v | Marple 2nd XV |
| Heaton Moor 2nd XV | v | Village Spartans |
| Leigh 3rd XV | v | Didsbury Toc H 3rd XV |
| Wythenshawe | v | Eccles RFC 4th XV |
| Saturday, 26 October 2024 |
| Aspull 3rd XV | v | Ashton-Under-Lyne 2nd XV |
| Bury 2nd XV | v | Wythenshawe |
| Didsbury Toc H 3rd XV | v | Congleton 2nd XV |
| Eccles RFC 4th XV | v | Heaton Moor 2nd XV |
| Manchester Hawks | v | Leigh 3rd XV |
| Village Spartans | v | Broughton |
| Saturday, 9 November 2024 |
| Ashton-Under-Lyne 2nd XV | v | Village Spartans |
| Broughton | v | Eccles RFC 4th XV |
| Congleton 2nd XV | v | Manchester Hawks |
| Heaton Moor 2nd XV | v | Bury 2nd XV |
| Leigh 3rd XV | v | Aspull 3rd XV |
| Marple 2nd XV | v | Didsbury Toc H 3rd XV |
| Saturday, 16 November 2024 |
| Aspull 3rd XV | v | Congleton 2nd XV |
| Bury 2nd XV | v | Broughton |
| Eccles RFC 4th XV | v | Ashton-Under-Lyne 2nd XV |
| Manchester Hawks | v | Marple 2nd XV |
| Village Spartans | v | Leigh 3rd XV |
| Wythenshawe | v | Heaton Moor 2nd XV |
| Saturday, 23 November 2024 |
| Ashton-Under-Lyne 2nd XV | v | Bury 2nd XV |
| Broughton | v | Wythenshawe |
| Congleton 2nd XV | v | Village Spartans |
| Didsbury Toc H 3rd XV | v | Manchester Hawks |
| Leigh 3rd XV | v | Eccles RFC 4th XV |
| Marple 2nd XV | v | Aspull 3rd XV |
| Saturday, 30 November 2024 |
| Aspull 3rd XV | v | Manchester Hawks |
| Bury 2nd XV | v | Congleton 2nd XV |
| Eccles RFC 4th XV | v | Marple 2nd XV |
| Heaton Moor 2nd XV | v | Ashton-Under-Lyne 2nd XV |
| Village Spartans | v | Didsbury Toc H 3rd XV |
| Wythenshawe | v | Leigh 3rd XV |
| Saturday, 7 December 2024 |
| Aspull 3rd XV | v | Didsbury Toc H 3rd XV |
| Bury 2nd XV | v | Leigh 3rd XV |
| Eccles RFC 4th XV | v | Congleton 2nd XV |
| Heaton Moor 2nd XV | v | Broughton |
| Village Spartans | v | Marple 2nd XV |
| Wythenshawe | v | Ashton-Under-Lyne 2nd XV |
| Saturday, 14 December 2024 |
| Ashton-Under-Lyne 2nd XV | v | Heaton Moor 2nd XV |
| Congleton 2nd XV | v | Bury 2nd XV |
| Didsbury Toc H 3rd XV | v | Village Spartans |
| Leigh 3rd XV | v | Wythenshawe |
| Manchester Hawks | v | Aspull 3rd XV |
| Marple 2nd XV | v | Eccles RFC 4th XV |
| Saturday, 21 December 2024 |
| Broughton | v | Ashton-Under-Lyne 2nd XV |
| Bury 2nd XV | v | Marple 2nd XV |
| Eccles RFC 4th XV | v | Didsbury Toc H 3rd XV |
| Heaton Moor 2nd XV | v | Leigh 3rd XV |
| Village Spartans | v | Manchester Hawks |
| Wythenshawe | v | Congleton 2nd XV |
| Saturday, 11 January 2025 |
| Ashton-Under-Lyne 2nd XV | v | Congleton 2nd XV |
| Broughton | v | Marple 2nd XV |
| Bury 2nd XV | v | Aspull 3rd XV |
| Eccles RFC 4th XV | v | Village Spartans |
| Heaton Moor 2nd XV | v | Didsbury Toc H 3rd XV |
| Wythenshawe | v | Manchester Hawks |
| Saturday, 18 January 2025 |
| Aspull 3rd XV | v | Wythenshawe |
| Congleton 2nd XV | v | Leigh 3rd XV |
| Didsbury Toc H 3rd XV | v | Broughton |
| Manchester Hawks | v | Heaton Moor 2nd XV |
| Marple 2nd XV | v | Ashton-Under-Lyne 2nd XV |
| Village Spartans | v | Bury 2nd XV |
| Saturday, 1 February 2025 |
| Ashton-Under-Lyne 2nd XV | v | Didsbury Toc H 3rd XV |
| Broughton | v | Manchester Hawks |
| Bury 2nd XV | v | Eccles RFC 4th XV |
| Heaton Moor 2nd XV | v | Aspull 3rd XV |
| Leigh 3rd XV | v | Marple 2nd XV |
| Wythenshawe | v | Village Spartans |
| Saturday, 8 February 2025 |
| Ashton-Under-Lyne 2nd XV | v | Broughton |
| Congleton 2nd XV | v | Wythenshawe |
| Didsbury Toc H 3rd XV | v | Eccles RFC 4th XV |
| Leigh 3rd XV | v | Heaton Moor 2nd XV |
| Manchester Hawks | v | Village Spartans |
| Marple 2nd XV | v | Bury 2nd XV |
| Saturday, 15 February 2025 |
| Aspull 3rd XV | v | Broughton |
| Didsbury Toc H 3rd XV | v | Leigh 3rd XV |
| Eccles RFC 4th XV | v | Wythenshawe |
| Manchester Hawks | v | Ashton-Under-Lyne 2nd XV |
| Marple 2nd XV | v | Congleton 2nd XV |
| Village Spartans | v | Heaton Moor 2nd XV |
| Saturday, 22 February 2025 |
| Broughton | v | Leigh 3rd XV |
| Bury 2nd XV | v | Didsbury Toc H 3rd XV |
| Eccles RFC 4th XV | v | Manchester Hawks |
| Heaton Moor 2nd XV | v | Congleton 2nd XV |
| Village Spartans | v | Aspull 3rd XV |
| Wythenshawe | v | Marple 2nd XV |
| Saturday, 1 March 2025 |
| Ashton-Under-Lyne 2nd XV | v | Aspull 3rd XV |
| Broughton | v | Village Spartans |
| Congleton 2nd XV | v | Didsbury Toc H 3rd XV |
| Heaton Moor 2nd XV | v | Eccles RFC 4th XV |
| Leigh 3rd XV | v | Manchester Hawks |
| Wythenshawe | v | Bury 2nd XV |
| Saturday, 8 March 2025 |
| Aspull 3rd XV | v | Leigh 3rd XV |
| Bury 2nd XV | v | Heaton Moor 2nd XV |
| Didsbury Toc H 3rd XV | v | Marple 2nd XV |
| Eccles RFC 4th XV | v | Broughton |
| Manchester Hawks | v | Congleton 2nd XV |
| Village Spartans | v | Ashton-Under-Lyne 2nd XV |
| Saturday, 22 March 2025 |
| Ashton-Under-Lyne 2nd XV | v | Eccles RFC 4th XV |
| Broughton | v | Bury 2nd XV |
| Congleton 2nd XV | v | Aspull 3rd XV |
| Heaton Moor 2nd XV | v | Wythenshawe |
| Leigh 3rd XV | v | Village Spartans |
| Marple 2nd XV | v | Manchester Hawks |
| Saturday, 5 April 2025 |
| Aspull 3rd XV | v | Marple 2nd XV |
| Bury 2nd XV | v | Ashton-Under-Lyne 2nd XV |
| Eccles RFC 4th XV | v | Leigh 3rd XV |
| Manchester Hawks | v | Didsbury Toc H 3rd XV |
| Village Spartans | v | Congleton 2nd XV |
| Wythenshawe | v | Broughton |
| Saturday, 26 April 2025 |
| Aspull 3rd XV | v | Eccles RFC 4th XV |
| Congleton 2nd XV | v | Broughton |
| Didsbury Toc H 3rd XV | v | Wythenshawe |
| Leigh 3rd XV | v | Ashton-Under-Lyne 2nd XV |
| Manchester Hawks | v | Bury 2nd XV |
| Marple 2nd XV | v | Heaton Moor 2nd XV |