| Saturday, 7 September 2024 |
| Liverpool Collegiate 2nd XV | 12 | 43 | Ellesmere Port 2nd XV |
| New Brighton 2nd XV | 41 | 0 | West Park (St Helens) 3rd XV |
| Sefton 2nd XV | 78 | 8 | Winnington Park 3rd XV |
| Widnes 3rd XV | Away Walkover | Anselmians Mavericks (3rd XV) |
| Saturday, 14 September 2024 |
| Ellesmere Port 2nd XV | 0 | 31 | New Brighton 2nd XV |
| Mossley Hill | 5 | 41 | Sefton 2nd XV |
| West Park (St Helens) 3rd XV | 41 | 34 | Anselmians Mavericks (3rd XV) |
| Widnes 3rd XV | 57 | 12 | Firwood Waterloo 3rd XV |
| Saturday, 21 September 2024 |
| Anselmians Mavericks (3rd XV) | 35 | 7 | Ellesmere Port 2nd XV |
| Firwood Waterloo 3rd XV | 53 | 12 | West Park (St Helens) 3rd XV |
| Liverpool Collegiate 2nd XV | 3 | 61 | Winnington Park 3rd XV |
| Prenton 2nd XV | 19 | 31 | Mossley Hill |
| Sefton 2nd XV | 68 | 12 | Helsby |
| Saturday, 28 September 2024 |
| Ellesmere Port 2nd XV | 27 | 21 | Firwood Waterloo 3rd XV |
| Helsby | 34 | 30 | Prenton 2nd XV |
| Mossley Hill | 34 | 17 | Liverpool Collegiate 2nd XV |
| West Park (St Helens) 3rd XV | Home Walkover | Widnes 3rd XV |
| Winnington Park 3rd XV | 0 | 59 | New Brighton 2nd XV |
| Saturday, 5 October 2024 |
| Helsby | 22 | 13 | Ellesmere Port 2nd XV |
| Liverpool Collegiate 2nd XV | Away Walkover | Firwood Waterloo 3rd XV |
| New Brighton 2nd XV | 43 | 12 | Anselmians Mavericks (3rd XV) |
| Prenton 2nd XV | Home Walkover | Widnes 3rd XV |
| Sefton 2nd XV | 47 | 24 | West Park (St Helens) 3rd XV |
| Saturday, 12 October 2024 |
| Anselmians Mavericks (3rd XV) | Home Walkover | Winnington Park 3rd XV |
| Liverpool Collegiate 2nd XV | 7 | 21 | Helsby |
| New Brighton 2nd XV | 29 | 15 | Mossley Hill |
| Prenton 2nd XV | 22 | 43 | Sefton 2nd XV |
| Widnes 3rd XV | 66 | 15 | Ellesmere Port 2nd XV |
| Saturday, 19 October 2024 |
| Ellesmere Port 2nd XV | 27 | 22 | West Park (St Helens) 3rd XV |
| Helsby | 32 | 31 | New Brighton 2nd XV |
| Mossley Hill | 14 | 14 | Anselmians Mavericks (3rd XV) |
| Sefton 2nd XV | 62 | 7 | Liverpool Collegiate 2nd XV |
| Winnington Park 3rd XV | 49 | 27 | Firwood Waterloo 3rd XV |
| Saturday, 26 October 2024 |
| Anselmians Mavericks (3rd XV) | 17 | 29 | Helsby |
| Firwood Waterloo 3rd XV | 41 | 31 | Mossley Hill |
| Liverpool Collegiate 2nd XV | 42 | 5 | Prenton 2nd XV |
| New Brighton 2nd XV | 24 | 29 | Sefton 2nd XV |
| Widnes 3rd XV | 20 | 12 | Winnington Park 3rd XV |
| Saturday, 9 November 2024 |
| Helsby | 61 | 28 | Firwood Waterloo 3rd XV |
| Mossley Hill | 26 | 0 | Widnes 3rd XV |
| Sefton 2nd XV | 47 | 12 | Anselmians Mavericks (3rd XV) |
| Winnington Park 3rd XV | 20 | 28 | West Park (St Helens) 3rd XV |
| Saturday, 16 November 2024 |
| Anselmians Mavericks (3rd XV) | 28 | 25 | Prenton 2nd XV |
| Ellesmere Port 2nd XV | 43 | 0 | Winnington Park 3rd XV |
| Firwood Waterloo 3rd XV | 24 | 41 | Sefton 2nd XV |
| New Brighton 2nd XV | 62 | 0 | Liverpool Collegiate 2nd XV |
| West Park (St Helens) 3rd XV | 15 | 64 | Mossley Hill |
| Widnes 3rd XV | 43 | 22 | Helsby |
| Saturday, 23 November 2024 |
| Mossley Hill | 19 | 43 | Ellesmere Port 2nd XV |
| Sefton 2nd XV | 52 | 0 | Widnes 3rd XV |
| Saturday, 30 November 2024 |
| Ellesmere Port 2nd XV | 17 | 17 | Sefton 2nd XV |
| Firwood Waterloo 3rd XV | 26 | 45 | New Brighton 2nd XV |
| West Park (St Helens) 3rd XV | Home Walkover | Prenton 2nd XV |
| Widnes 3rd XV | Home Walkover | Liverpool Collegiate 2nd XV |
| Winnington Park 3rd XV | Away Walkover | Mossley Hill |
| Saturday, 14 December 2024 |
| Mossley Hill | 10 | 46 | Winnington Park 3rd XV |
| New Brighton 2nd XV | 67 | 5 | Firwood Waterloo 3rd XV |
| Sefton 2nd XV | 53 | 12 | Ellesmere Port 2nd XV |
| West Park (St Helens) 3rd XV | Home Walkover | Prenton 2nd XV |
| Widnes 3rd XV | 31 | 17 | Liverpool Collegiate 2nd XV |
| Saturday, 21 December 2024 |
| Ellesmere Port 2nd XV | 22 | 8 | Prenton 2nd XV |
| Firwood Waterloo 3rd XV | 20 | 17 | Anselmians Mavericks (3rd XV) |
| West Park (St Helens) 3rd XV | 21 | 12 | Liverpool Collegiate 2nd XV |
| Widnes 3rd XV | 0 | 41 | New Brighton 2nd XV |
| Winnington Park 3rd XV | 12 | 63 | Helsby |
| Saturday, 4 January 2025 |
| Winnington Park 3rd XV | 8 | 51 | Prenton 2nd XV |
| Saturday, 18 January 2025 |
| Firwood Waterloo 3rd XV | 28 | 36 | Ellesmere Port 2nd XV |
| Liverpool Collegiate 2nd XV | 31 | 27 | Mossley Hill |
| New Brighton 2nd XV | 61 | 5 | Winnington Park 3rd XV |
| Prenton 2nd XV | 3 | 46 | Helsby |
| West Park (St Helens) 3rd XV | 27 | 17 | Widnes 3rd XV |
| Saturday, 25 January 2025 |
| Liverpool Collegiate 2nd XV | v | Anselmians Mavericks (3rd XV) |
| West Park (St Helens) 3rd XV | v | Sefton 2nd XV |
| Saturday, 1 February 2025 |
| Ellesmere Port 2nd XV | v | Widnes 3rd XV |
| Helsby | v | Liverpool Collegiate 2nd XV |
| Mossley Hill | v | New Brighton 2nd XV |
| Sefton 2nd XV | v | Prenton 2nd XV |
| Saturday, 8 February 2025 |
| Anselmians Mavericks (3rd XV) | v | Firwood Waterloo 3rd XV |
| Helsby | v | Winnington Park 3rd XV |
| Liverpool Collegiate 2nd XV | v | West Park (St Helens) 3rd XV |
| New Brighton 2nd XV | v | Widnes 3rd XV |
| Prenton 2nd XV | v | Ellesmere Port 2nd XV |
| Saturday, 15 February 2025 |
| Anselmians Mavericks (3rd XV) | v | Mossley Hill |
| Firwood Waterloo 3rd XV | v | Winnington Park 3rd XV |
| Liverpool Collegiate 2nd XV | v | Sefton 2nd XV |
| New Brighton 2nd XV | v | Helsby |
| West Park (St Helens) 3rd XV | v | Ellesmere Port 2nd XV |
| Widnes 3rd XV | v | Prenton 2nd XV |
| Saturday, 22 February 2025 |
| Anselmians Mavericks (3rd XV) | v | Widnes 3rd XV |
| Ellesmere Port 2nd XV | v | Liverpool Collegiate 2nd XV |
| Mossley Hill | v | Helsby |
| Prenton 2nd XV | v | Firwood Waterloo 3rd XV |
| West Park (St Helens) 3rd XV | v | New Brighton 2nd XV |
| Winnington Park 3rd XV | v | Sefton 2nd XV |
| Saturday, 1 March 2025 |
| Helsby | v | Anselmians Mavericks (3rd XV) |
| Mossley Hill | v | Firwood Waterloo 3rd XV |
| Prenton 2nd XV | v | Liverpool Collegiate 2nd XV |
| Sefton 2nd XV | v | New Brighton 2nd XV |
| Winnington Park 3rd XV | v | Widnes 3rd XV |
| Friday, 7 March 2025 |
| New Brighton 2nd XV | v | Prenton 2nd XV |
| New Brighton 2nd XV | v | Prenton 2nd XV |
| Saturday, 8 March 2025 |
| Anselmians Mavericks (3rd XV) | v | Sefton 2nd XV |
| Firwood Waterloo 3rd XV | v | Helsby |
| West Park (St Helens) 3rd XV | v | Winnington Park 3rd XV |
| Widnes 3rd XV | v | Mossley Hill |
| Saturday, 15 March 2025 |
| Anselmians Mavericks (3rd XV) | v | Winnington Park 3rd XV |
| Ellesmere Port 2nd XV | v | Helsby |
| Firwood Waterloo 3rd XV | v | Liverpool Collegiate 2nd XV |
| Mossley Hill | v | Prenton 2nd XV |
| Saturday, 22 March 2025 |
| Helsby | v | Widnes 3rd XV |
| Liverpool Collegiate 2nd XV | v | New Brighton 2nd XV |
| Mossley Hill | v | West Park (St Helens) 3rd XV |
| Prenton 2nd XV | v | Anselmians Mavericks (3rd XV) |
| Sefton 2nd XV | v | Firwood Waterloo 3rd XV |
| Winnington Park 3rd XV | v | Ellesmere Port 2nd XV |
| Saturday, 29 March 2025 |
| Ellesmere Port 2nd XV | v | Anselmians Mavericks (3rd XV) |
| Helsby | v | Mossley Hill |
| Winnington Park 3rd XV | v | Liverpool Collegiate 2nd XV |
| Saturday, 5 April 2025 |
| Anselmians Mavericks (3rd XV) | v | Liverpool Collegiate 2nd XV |
| Ellesmere Port 2nd XV | v | Mossley Hill |
| Firwood Waterloo 3rd XV | v | Prenton 2nd XV |
| Helsby | v | West Park (St Helens) 3rd XV |
| Helsby | v | West Park (St Helens) 3rd XV |
| Widnes 3rd XV | v | Sefton 2nd XV |
| Saturday, 12 April 2025 |
| Anselmians Mavericks (3rd XV) | v | New Brighton 2nd XV |
| Helsby | v | Sefton 2nd XV |
| West Park (St Helens) 3rd XV | v | Firwood Waterloo 3rd XV |
| Saturday, 26 April 2025 |
| Anselmians Mavericks (3rd XV) | v | West Park (St Helens) 3rd XV |
| Firwood Waterloo 3rd XV | v | Widnes 3rd XV |
| New Brighton 2nd XV | v | Ellesmere Port 2nd XV |
| Prenton 2nd XV | v | Winnington Park 3rd XV |
| Sefton 2nd XV | v | Mossley Hill |