| Saturday, 7 September 2024 |
| Helsby | Postponed | Mossley Hill |
| Liverpool Collegiate 2nd XV | 12 | 36 | Ellesmere Port 2nd XV |
| New Brighton 2nd XV | 41 | 0 | West Park (St Helens) 3rd XV |
| Sefton 2nd XV | 78 | 8 | Winnington Park 3rd XV |
| Widnes 3rd XV | Away Walkover | Anselmians Mavericks (3rd XV) |
| Saturday, 14 September 2024 |
| Ellesmere Port 2nd XV | v | New Brighton 2nd XV |
| Mossley Hill | v | Sefton 2nd XV |
| West Park (St Helens) 3rd XV | v | Anselmians Mavericks (3rd XV) |
| Widnes 3rd XV | v | Firwood Waterloo 3rd XV |
| Winnington Park 3rd XV | v | Prenton 2nd XV |
| Saturday, 21 September 2024 |
| Anselmians Mavericks (3rd XV) | v | Ellesmere Port 2nd XV |
| Firwood Waterloo 3rd XV | v | West Park (St Helens) 3rd XV |
| Liverpool Collegiate 2nd XV | v | Winnington Park 3rd XV |
| Prenton 2nd XV | v | Mossley Hill |
| Sefton 2nd XV | v | Helsby |
| Saturday, 28 September 2024 |
| Ellesmere Port 2nd XV | v | Firwood Waterloo 3rd XV |
| Helsby | v | Prenton 2nd XV |
| Mossley Hill | v | Liverpool Collegiate 2nd XV |
| West Park (St Helens) 3rd XV | v | Widnes 3rd XV |
| Winnington Park 3rd XV | v | New Brighton 2nd XV |
| Saturday, 5 October 2024 |
| Helsby | v | Ellesmere Port 2nd XV |
| Liverpool Collegiate 2nd XV | v | Firwood Waterloo 3rd XV |
| New Brighton 2nd XV | v | Anselmians Mavericks (3rd XV) |
| Prenton 2nd XV | v | Widnes 3rd XV |
| Sefton 2nd XV | v | West Park (St Helens) 3rd XV |
| Saturday, 12 October 2024 |
| Anselmians Mavericks (3rd XV) | v | Winnington Park 3rd XV |
| Liverpool Collegiate 2nd XV | v | Helsby |
| New Brighton 2nd XV | v | Mossley Hill |
| Prenton 2nd XV | v | Sefton 2nd XV |
| Widnes 3rd XV | v | Ellesmere Port 2nd XV |
| Saturday, 19 October 2024 |
| Ellesmere Port 2nd XV | v | West Park (St Helens) 3rd XV |
| Helsby | v | New Brighton 2nd XV |
| Mossley Hill | v | Anselmians Mavericks (3rd XV) |
| Sefton 2nd XV | v | Liverpool Collegiate 2nd XV |
| Winnington Park 3rd XV | v | Firwood Waterloo 3rd XV |
| Saturday, 26 October 2024 |
| Anselmians Mavericks (3rd XV) | v | Helsby |
| Firwood Waterloo 3rd XV | v | Mossley Hill |
| Liverpool Collegiate 2nd XV | v | Prenton 2nd XV |
| New Brighton 2nd XV | v | Sefton 2nd XV |
| Widnes 3rd XV | v | Winnington Park 3rd XV |
| Saturday, 9 November 2024 |
| Helsby | v | Firwood Waterloo 3rd XV |
| Mossley Hill | v | Widnes 3rd XV |
| Prenton 2nd XV | v | New Brighton 2nd XV |
| Sefton 2nd XV | v | Anselmians Mavericks (3rd XV) |
| Winnington Park 3rd XV | v | West Park (St Helens) 3rd XV |
| Saturday, 16 November 2024 |
| Anselmians Mavericks (3rd XV) | v | Prenton 2nd XV |
| Ellesmere Port 2nd XV | v | Winnington Park 3rd XV |
| Firwood Waterloo 3rd XV | v | Sefton 2nd XV |
| New Brighton 2nd XV | v | Liverpool Collegiate 2nd XV |
| West Park (St Helens) 3rd XV | v | Mossley Hill |
| Widnes 3rd XV | v | Helsby |
| Saturday, 23 November 2024 |
| Helsby | v | West Park (St Helens) 3rd XV |
| Liverpool Collegiate 2nd XV | v | Anselmians Mavericks (3rd XV) |
| Mossley Hill | v | Ellesmere Port 2nd XV |
| Prenton 2nd XV | v | Firwood Waterloo 3rd XV |
| Sefton 2nd XV | v | Widnes 3rd XV |
| Saturday, 30 November 2024 |
| Ellesmere Port 2nd XV | v | Sefton 2nd XV |
| Firwood Waterloo 3rd XV | v | New Brighton 2nd XV |
| West Park (St Helens) 3rd XV | v | Prenton 2nd XV |
| Widnes 3rd XV | v | Liverpool Collegiate 2nd XV |
| Winnington Park 3rd XV | v | Mossley Hill |
| Saturday, 7 December 2024 |
| Anselmians Mavericks (3rd XV) | v | New Brighton 2nd XV |
| Ellesmere Port 2nd XV | v | Helsby |
| Firwood Waterloo 3rd XV | v | Liverpool Collegiate 2nd XV |
| West Park (St Helens) 3rd XV | v | Sefton 2nd XV |
| Widnes 3rd XV | v | Prenton 2nd XV |
| Saturday, 14 December 2024 |
| Liverpool Collegiate 2nd XV | v | Widnes 3rd XV |
| Mossley Hill | v | Winnington Park 3rd XV |
| New Brighton 2nd XV | v | Firwood Waterloo 3rd XV |
| Prenton 2nd XV | v | West Park (St Helens) 3rd XV |
| Sefton 2nd XV | v | Ellesmere Port 2nd XV |
| Saturday, 21 December 2024 |
| Ellesmere Port 2nd XV | v | Prenton 2nd XV |
| Firwood Waterloo 3rd XV | v | Anselmians Mavericks (3rd XV) |
| West Park (St Helens) 3rd XV | v | Liverpool Collegiate 2nd XV |
| Widnes 3rd XV | v | New Brighton 2nd XV |
| Winnington Park 3rd XV | v | Helsby |
| Saturday, 11 January 2025 |
| Ellesmere Port 2nd XV | v | Anselmians Mavericks (3rd XV) |
| Helsby | v | Sefton 2nd XV |
| Mossley Hill | v | Prenton 2nd XV |
| West Park (St Helens) 3rd XV | v | Firwood Waterloo 3rd XV |
| Winnington Park 3rd XV | v | Liverpool Collegiate 2nd XV |
| Saturday, 18 January 2025 |
| Firwood Waterloo 3rd XV | v | Ellesmere Port 2nd XV |
| Liverpool Collegiate 2nd XV | v | Mossley Hill |
| New Brighton 2nd XV | v | Winnington Park 3rd XV |
| Prenton 2nd XV | v | Helsby |
| Widnes 3rd XV | v | West Park (St Helens) 3rd XV |
| Saturday, 1 February 2025 |
| Ellesmere Port 2nd XV | v | Widnes 3rd XV |
| Helsby | v | Liverpool Collegiate 2nd XV |
| Mossley Hill | v | New Brighton 2nd XV |
| Sefton 2nd XV | v | Prenton 2nd XV |
| Winnington Park 3rd XV | v | Anselmians Mavericks (3rd XV) |
| Saturday, 8 February 2025 |
| Anselmians Mavericks (3rd XV) | v | Firwood Waterloo 3rd XV |
| Helsby | v | Winnington Park 3rd XV |
| Liverpool Collegiate 2nd XV | v | West Park (St Helens) 3rd XV |
| New Brighton 2nd XV | v | Widnes 3rd XV |
| Prenton 2nd XV | v | Ellesmere Port 2nd XV |
| Saturday, 15 February 2025 |
| Anselmians Mavericks (3rd XV) | v | Mossley Hill |
| Firwood Waterloo 3rd XV | v | Winnington Park 3rd XV |
| Liverpool Collegiate 2nd XV | v | Sefton 2nd XV |
| New Brighton 2nd XV | v | Helsby |
| West Park (St Helens) 3rd XV | v | Ellesmere Port 2nd XV |
| Saturday, 22 February 2025 |
| Anselmians Mavericks (3rd XV) | v | Widnes 3rd XV |
| Ellesmere Port 2nd XV | v | Liverpool Collegiate 2nd XV |
| Mossley Hill | v | Helsby |
| West Park (St Helens) 3rd XV | v | New Brighton 2nd XV |
| Winnington Park 3rd XV | v | Sefton 2nd XV |
| Saturday, 1 March 2025 |
| Helsby | v | Anselmians Mavericks (3rd XV) |
| Mossley Hill | v | Firwood Waterloo 3rd XV |
| Prenton 2nd XV | v | Liverpool Collegiate 2nd XV |
| Sefton 2nd XV | v | New Brighton 2nd XV |
| Winnington Park 3rd XV | v | Widnes 3rd XV |
| Saturday, 8 March 2025 |
| Anselmians Mavericks (3rd XV) | v | Sefton 2nd XV |
| Firwood Waterloo 3rd XV | v | Helsby |
| New Brighton 2nd XV | v | Prenton 2nd XV |
| West Park (St Helens) 3rd XV | v | Winnington Park 3rd XV |
| Widnes 3rd XV | v | Mossley Hill |
| Saturday, 22 March 2025 |
| Helsby | v | Widnes 3rd XV |
| Liverpool Collegiate 2nd XV | v | New Brighton 2nd XV |
| Mossley Hill | v | West Park (St Helens) 3rd XV |
| Prenton 2nd XV | v | Anselmians Mavericks (3rd XV) |
| Sefton 2nd XV | v | Firwood Waterloo 3rd XV |
| Winnington Park 3rd XV | v | Ellesmere Port 2nd XV |
| Saturday, 5 April 2025 |
| Anselmians Mavericks (3rd XV) | v | Liverpool Collegiate 2nd XV |
| Ellesmere Port 2nd XV | v | Mossley Hill |
| Firwood Waterloo 3rd XV | v | Prenton 2nd XV |
| West Park (St Helens) 3rd XV | v | Helsby |
| Widnes 3rd XV | v | Sefton 2nd XV |
| Saturday, 26 April 2025 |
| Anselmians Mavericks (3rd XV) | v | West Park (St Helens) 3rd XV |
| Firwood Waterloo 3rd XV | v | Widnes 3rd XV |
| New Brighton 2nd XV | v | Ellesmere Port 2nd XV |
| Prenton 2nd XV | v | Winnington Park 3rd XV |
| Sefton 2nd XV | v | Mossley Hill |