| Saturday, 16 January 2021 |
| Bury 3rd XV | Postponed | Colne & Nelson 2nd XV |
| Garstang Blues (2nd XV) | Postponed | Blackpool |
| Preston Grasshoppers 5th XV | Postponed | Lostock |
| Saturday, 23 January 2021 |
| Blackpool | Postponed | Bury 3rd XV |
| Colne & Nelson 2nd XV | Postponed | Clitheroe 2nd XV |
| Lostock | Postponed | Garstang Blues (2nd XV) |
| Saturday, 30 January 2021 |
| Bury 3rd XV | Postponed | Lostock |
| Clitheroe 2nd XV | Postponed | Blackpool |
| Garstang Blues (2nd XV) | Postponed | Preston Grasshoppers 5th XV |
| Saturday, 6 February 2021 |
| Blackpool | Postponed | Colne & Nelson 2nd XV |
| Lostock | Postponed | Clitheroe 2nd XV |
| Preston Grasshoppers 5th XV | Postponed | Bury 3rd XV |
| Saturday, 13 February 2021 |
| Bury 3rd XV | Postponed | Garstang Blues (2nd XV) |
| Clitheroe 2nd XV | Postponed | Preston Grasshoppers 5th XV |
| Colne & Nelson 2nd XV | Postponed | Lostock |
| Saturday, 20 February 2021 |
| Garstang Blues (2nd XV) | Postponed | Clitheroe 2nd XV |
| Lostock | Postponed | Blackpool |
| Preston Grasshoppers 5th XV | Postponed | Colne & Nelson 2nd XV |
| Saturday, 27 February 2021 |
| Blackpool | Postponed | Preston Grasshoppers 5th XV |
| Clitheroe 2nd XV | Postponed | Bury 3rd XV |
| Colne & Nelson 2nd XV | Postponed | Garstang Blues (2nd XV) |
| Saturday, 13 March 2021 |
| Bury 3rd XV | v | Blackpool |
| Clitheroe 2nd XV | v | Colne & Nelson 2nd XV |
| Garstang Blues (2nd XV) | v | Lostock |
| Saturday, 20 March 2021 |
| Blackpool | v | Clitheroe 2nd XV |
| Lostock | v | Bury 3rd XV |
| Preston Grasshoppers 5th XV | v | Garstang Blues (2nd XV) |
| Saturday, 27 March 2021 |
| Bury 3rd XV | v | Preston Grasshoppers 5th XV |
| Clitheroe 2nd XV | v | Lostock |
| Colne & Nelson 2nd XV | v | Blackpool |
| Saturday, 10 April 2021 |
| Garstang Blues (2nd XV) | v | Bury 3rd XV |
| Lostock | v | Colne & Nelson 2nd XV |
| Preston Grasshoppers 5th XV | v | Clitheroe 2nd XV |
| Saturday, 17 April 2021 |
| Blackpool | v | Lostock |
| Clitheroe 2nd XV | v | Garstang Blues (2nd XV) |
| Colne & Nelson 2nd XV | v | Preston Grasshoppers 5th XV |
| Saturday, 24 April 2021 |
| Bury 3rd XV | v | Clitheroe 2nd XV |
| Garstang Blues (2nd XV) | v | Colne & Nelson 2nd XV |
| Preston Grasshoppers 5th XV | v | Blackpool |
| Saturday, 1 May 2021 |
| Blackpool | v | Garstang Blues (2nd XV) |
| Colne & Nelson 2nd XV | v | Bury 3rd XV |
| Lostock | v | Preston Grasshoppers 5th XV |